Explore ERAP2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
Target ID |
GM-T65818
|
Target Name |
ERAP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
64167
|
Gene ID |
100073223 (Equus caballus), 100856345 (Canis lupus familiaris), 513572 (Bos taurus), 64167 (Homo sapiens) 700118 (Macaca mulatta)
|
Target Alternative Names |
ERAP2,Endoplasmic reticulum aminopeptidase 2,L-RAP,LRAP,Leukocyte-derived arginine aminopeptidase (L-RAP)
|
Uniprot Accession |
A6QPT7,Q6P179
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000024465, ENSBTAG00000039275, ENSG00000164308, ENSMMUG00000011043
|
Target Classification |
|
ERAP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo64167 | Pre-made Human ERAP2/LRAP/L-RAP siRNA oligo Duplex | 64167 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo700118 | Pre-made Cynomolgus/Rhesus macaque ERAP2 siRNA oligo Duplex | 700118 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo100856345 | Pre-made Dog/Canine ERAP2 siRNA oligo Duplex | 100856345 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo513572 | Pre-made Bovines/Cattle ERAP2 siRNA oligo Duplex | 513572 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100073223 | Pre-made Equine/Horse ERAP2 siRNA oligo Duplex | 100073223 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ERAP2 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T65818-Ab | Human | Anti-Human ERAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-T65818-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ERAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-T65818-Ab | Dog/Canine | Anti-Dog/Canine ERAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-T65818-Ab | Bovines/Cattle | Anti-Bovines/Cattle ERAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-T65818-Ab | Equine/Horse | Anti-Equine/Horse ERAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ERAP2 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T65818-Ag | Human | Human ERAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-T65818-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ERAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-T65818-Ag | Dog/Canine | Dog/Canine ERAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-T65818-Ag | Bovines/Cattle | Bovines/Cattle ERAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-T65818-Ag | Equine/Horse | Equine/Horse ERAP2 VLP (virus-like particle) | HEK293 | Products Developing |