Explore APJ/APLNR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]
| Target ID |
GM-T65783
|
| Target Name |
APJ/APLNR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
187
|
| Gene ID |
100066889 (Equus caballus), 101088782 (Felis catus), 187 (Homo sapiens), 23796 (Mus musculus)
483497 (Canis lupus familiaris), 615435 (Bos taurus), 706823 (Macaca mulatta), 83518 (Rattus norvegicus)
|
| Target Alternative Names |
AGTRL1,APJ,APJR,APLNR,Agtrl1,Angiotensin receptor-like 1,Apelin receptor,Apj,Aplnr,G-protein coupled receptor APJ,G-protein coupled receptor HG11,HG11,msr/apj
|
| Uniprot Accession |
P35414,Q9WV08,O97666,Q9JHG3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000004658, ENSG00000134817, ENSMUSG00000044338, ENSBTAG00000027516, ENSMMUG00000010627
|
| Target Classification |
GPCR
|
Pre-made viral vector of APJ/APLNR cDNA Clones/ORF Plasmid
APJ/APLNR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo187 | Pre-made Human APLNR/APJ/APJR siRNA oligo Duplex | 187 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83518 | Pre-made Rat Aplnr/Apj/Agtrl1 siRNA oligo Duplex | 83518 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23796 | Pre-made Mouse Aplnr/APJ/Agtrl1 siRNA oligo Duplex | 23796 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706823 | Pre-made Cynomolgus/Rhesus macaque APLNR/APJ/AGTRL1 siRNA oligo Duplex | 706823 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088782 | Pre-made Cat/Feline APLNR siRNA oligo Duplex | 101088782 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483497 | Pre-made Dog/Canine APLNR/AGTRL1 siRNA oligo Duplex | 483497 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615435 | Pre-made Bovines/Cattle APLNR/AGTRL1 siRNA oligo Duplex | 615435 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066889 | Pre-made Equine/Horse APLNR siRNA oligo Duplex | 100066889 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
APJ/APLNR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T65783-Ab | Human | Anti-Human APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T65783-Ab | Rat | Anti-Rat APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T65783-Ab | Mouse | Anti-Mouse APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T65783-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T65783-Ab | Cat/Feline | Anti-Cat/Feline APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T65783-Ab | Dog/Canine | Anti-Dog/Canine APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T65783-Ab | Bovines/Cattle | Anti-Bovines/Cattle APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T65783-Ab | Equine/Horse | Anti-Equine/Horse APJ/APLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
APJ/APLNR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T65783-Ag | Human | Human APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T65783-Ag | Rat | Rat APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T65783-Ag | Mouse | Mouse APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T65783-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T65783-Ag | Cat/Feline | Cat/Feline APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T65783-Ag | Dog/Canine | Dog/Canine APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T65783-Ag | Bovines/Cattle | Bovines/Cattle APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T65783-Ag | Equine/Horse | Equine/Horse APJ/APLNR VLP (virus-like particle) | HEK293 | Products Developing |
