ADH1A Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

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Target sublocation: Transmembrane Protein.
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Target ID GM-T65570
Target Name ADH1A
Gene Group ldentifer
(Target Gene ID in Homo species)
124
Target Alternative Names ADH1,ADH1A,Alcohol dehydrogenase 1A,Alcohol dehydrogenase subunit alpha
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease from KEGG Metabolic pathways, Alcoholic liver disease, Retinol metabolism, Drug metabolism - cytochrome P450