GPER1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore GPER1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]

Target ID GM-T65236
Target Name GPER1
Gene Group ldentifer
(Target Gene ID in Homo species)
2852
Gene ID 101085767 (Felis catus), 102148430 (Equus caballus), 171104 (Rattus norvegicus), 2852 (Homo sapiens)
480808 (Canis lupus familiaris), 527831 (Bos taurus), 696625 (Macaca mulatta), 76854 (Mus musculus)
Target Alternative Names 6330420K13Rik,CEPR,CMKRL2,Ceprl,Chemoattractant receptor-like 2,DRY12,FEG-1,Flow-induced endothelial G-protein coupled receptor 1 (FEG-1),G protein-coupled estrogen receptor 1,G-protein coupled estrogen receptor 1,G-protein coupled receptor 30,GPCR-Br,GPER,GPER1,GPR30,GPR41,Gper,Gper1,Gpr30,IL8-related receptor DRY12,LERGU,LERGU2,LyGPR,Lymphocyte-derived G-protein coupled receptor (LYGPR),Membrane estrogen receptor (mER),mER
Uniprot Accession O08878,Q99527,F7EQ49,Q8BMP4
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Endocrine resistance, GnRH secretion
Gene Ensembl ENSECAG00000001177, ENSG00000164850, ENSCAFG00845008614, ENSBTAG00000060277, ENSMMUG00000007209, ENSMUSG00000053647
Target Classification GPCR, Tumor-associated antigen (TAA)


Pre-made viral vector of GPER1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV000420Human GPER1/CEPR/CMKRL2 Lentivirus plasmidNM_001039966.12852HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV002326Human GPER1/CEPR/CMKRL2 Lentivirus plasmidNM_001039966.12852HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMLV000420Human GPER1/CEPR/CMKRL2 Lentivirus particleNM_001039966.12852HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV002326Human GPER1/CEPR/CMKRL2 Lentivirus particleNM_001039966.12852HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
pGMLPm001438Mouse Gper1/6330420K13Rik/Ceprl Lentivirus plasmidNM_02977176854MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm001438Mouse Gper1/6330420K13Rik/Ceprl Lentivirus particleNM_02977176854MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


GPER1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo2852Pre-made Human GPER1/mER/CEPR siRNA oligo Duplex2852HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo171104Pre-made Rat Gper1/Gper/GPR41 siRNA oligo Duplex171104RatIn-vitro grade; in-vivo gradeDetail
pGMoligo76854Pre-made Mouse Gper1/Gper/Ceprl siRNA oligo Duplex76854MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo696625Pre-made Cynomolgus/Rhesus macaque GPER1/GPER/GPR30 siRNA oligo Duplex696625Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101085767Pre-made Cat/Feline GPER1/GPER siRNA oligo Duplex101085767Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo480808Pre-made Dog/Canine GPER1/GPER/GPR30 siRNA oligo Duplex480808Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo527831Pre-made Bovines/Cattle GPER1/GPER siRNA oligo Duplex527831Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo102148430Pre-made Equine/Horse GPER1 siRNA oligo Duplex102148430Equine/HorseIn-vitro grade; in-vivo gradeDetail


GPER1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T65236-AbHumanAnti-Human GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T65236-AbRatAnti-Rat GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T65236-AbMouseAnti-Mouse GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T65236-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T65236-AbCat/FelineAnti-Cat/Feline GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T65236-AbDog/CanineAnti-Dog/Canine GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T65236-AbBovines/CattleAnti-Bovines/Cattle GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T65236-AbEquine/HorseAnti-Equine/Horse GPER1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


GPER1 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T65236-AgHumanHuman GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T65236-AgRatRat GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T65236-AgMouseMouse GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T65236-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T65236-AgCat/FelineCat/Feline GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T65236-AgDog/CanineDog/Canine GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T65236-AgBovines/CattleBovines/Cattle GPER1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T65236-AgEquine/HorseEquine/Horse GPER1 VLP (virus-like particle)HEK293Products Developing