Explore EPOR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
| Target ID |
GM-T65197
|
| Target Name |
EPOR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2057
|
| Gene ID |
100057022 (Equus caballus), 101081364 (Felis catus), 13857 (Mus musculus), 2057 (Homo sapiens)
24336 (Rattus norvegicus), 281144 (Bos taurus), 484943 (Canis lupus familiaris), 714546 (Macaca mulatta)
|
| Target Alternative Names |
EPO-R,EPOR,Epor,Erythropoietin receptor
|
| Uniprot Accession |
P14753,P19235,Q07303,Q2KL21
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000008049, ENSMUSG00000006235, ENSG00000187266, ENSBTAG00000008197, ENSCAFG00845019440, ENSMMUG00000038989
|
| Target Classification |
Cytokine Receptor, Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of EPOR cDNA Clones/ORF Plasmid
EPOR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2057 | Pre-made Human EPOR/EPO-R siRNA oligo Duplex | 2057 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24336 | Pre-made Rat Epor siRNA oligo Duplex | 24336 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13857 | Pre-made Mouse Epor siRNA oligo Duplex | 13857 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714546 | Pre-made Cynomolgus/Rhesus macaque EPOR siRNA oligo Duplex | 714546 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081364 | Pre-made Cat/Feline EPOR siRNA oligo Duplex | 101081364 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484943 | Pre-made Dog/Canine EPOR/EPO-R siRNA oligo Duplex | 484943 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281144 | Pre-made Bovines/Cattle EPOR siRNA oligo Duplex | 281144 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057022 | Pre-made Equine/Horse EPOR siRNA oligo Duplex | 100057022 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EPOR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T65197-Ab | Human | Anti-Human EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T65197-Ab | Rat | Anti-Rat EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T65197-Ab | Mouse | Anti-Mouse EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T65197-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T65197-Ab | Cat/Feline | Anti-Cat/Feline EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T65197-Ab | Dog/Canine | Anti-Dog/Canine EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T65197-Ab | Bovines/Cattle | Anti-Bovines/Cattle EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T65197-Ab | Equine/Horse | Anti-Equine/Horse EPOR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EPOR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T65197-Ag | Human | Human EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T65197-Ag | Rat | Rat EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T65197-Ag | Mouse | Mouse EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T65197-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T65197-Ag | Cat/Feline | Cat/Feline EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T65197-Ag | Dog/Canine | Dog/Canine EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T65197-Ag | Bovines/Cattle | Bovines/Cattle EPOR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T65197-Ag | Equine/Horse | Equine/Horse EPOR VLP (virus-like particle) | HEK293 | Products Developing |
