Explore HCN2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
| Target ID |
GM-T65005
|
| Target Name |
HCN2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
610
|
| Gene ID |
100297361 (Bos taurus), 100425114 (Macaca mulatta), 101090996 (Felis catus), 111774151 (Equus caballus)
114244 (Rattus norvegicus), 15166 (Mus musculus), 448791 (Canis lupus familiaris), 610 (Homo sapiens)
|
| Target Alternative Names |
BCNG-2,BCNG2,Brain cyclic nucleotide-gated channel 2 (BCNG-2),EIG17,FEB2,GEFSP11,HAC-1,HAC1,HCN2,Hcn2,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2,trls
|
| Uniprot Accession |
Q9JKA9,O88703,Q9UL51
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, GnRH secretion
|
| Gene Ensembl |
ENSBTAG00000015050, ENSMMUG00000012768, ENSECAG00000039849, ENSMUSG00000020331, ENSCAFG00845015054, ENSG00000099822
|
| Target Classification |
Ion Channel
|
Pre-made viral vector of HCN2 cDNA Clones/ORF Plasmid
HCN2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo610 | Pre-made Human HCN2/FEB2/BCNG2 siRNA oligo Duplex | 610 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114244 | Pre-made Rat Hcn2 siRNA oligo Duplex | 114244 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15166 | Pre-made Mouse Hcn2/HAC1/trls siRNA oligo Duplex | 15166 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100425114 | Pre-made Cynomolgus/Rhesus macaque HCN2 siRNA oligo Duplex | 100425114 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090996 | Pre-made Cat/Feline HCN2 siRNA oligo Duplex | 101090996 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo448791 | Pre-made Dog/Canine HCN2 siRNA oligo Duplex | 448791 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100297361 | Pre-made Bovines/Cattle HCN2 siRNA oligo Duplex | 100297361 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111774151 | Pre-made Equine/Horse HCN2 siRNA oligo Duplex | 111774151 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HCN2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T65005-Ab | Human | Anti-Human HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T65005-Ab | Rat | Anti-Rat HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T65005-Ab | Mouse | Anti-Mouse HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T65005-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T65005-Ab | Cat/Feline | Anti-Cat/Feline HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T65005-Ab | Dog/Canine | Anti-Dog/Canine HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T65005-Ab | Bovines/Cattle | Anti-Bovines/Cattle HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T65005-Ab | Equine/Horse | Anti-Equine/Horse HCN2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HCN2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T65005-Ag | Human | Human HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T65005-Ag | Rat | Rat HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T65005-Ag | Mouse | Mouse HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T65005-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T65005-Ag | Cat/Feline | Cat/Feline HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T65005-Ag | Dog/Canine | Dog/Canine HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T65005-Ag | Bovines/Cattle | Bovines/Cattle HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T65005-Ag | Equine/Horse | Equine/Horse HCN2 VLP (virus-like particle) | HEK293 | Products Developing |
