Explore SSTR5 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]
| Target ID |
GM-T64830
|
| Target Name |
SSTR5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6755
|
| Gene ID |
100067398 (Equus caballus), 101090317 (Felis catus), 106994905 (Macaca mulatta), 20609 (Mus musculus) 25354 (Rattus norvegicus), 403454 (Canis lupus familiaris), 510344 (Bos taurus), 6755 (Homo sapiens)
|
| Target Alternative Names |
SS-5-R,SS5-R,SS5R,SST5,SSTR5,Smstr5,Somato,Somatostatin receptor type 5,Sstr5,sst5
|
| Uniprot Accession |
O08858,P30938,F1MV99,P35346
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000005022, ENSMMUG00000002896, ENSMUSG00000050824, ENSCAFG00845024735, ENSBTAG00000039974, ENSG00000162009
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
Pre-made viral vector of SSTR5 cDNA Clones/ORF Plasmid
SSTR5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6755 | Pre-made Human SSTR5/SST5/SS-5-R siRNA oligo Duplex | 6755 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25354 | Pre-made Rat Sstr5/Smstr5/Somato siRNA oligo Duplex | 25354 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20609 | Pre-made Mouse Sstr5/sst5/Smstr5 siRNA oligo Duplex | 20609 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106994905 | Pre-made Cynomolgus/Rhesus macaque SSTR5 siRNA oligo Duplex | 106994905 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090317 | Pre-made Cat/Feline SSTR5 siRNA oligo Duplex | 101090317 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403454 | Pre-made Dog/Canine SSTR5 siRNA oligo Duplex | 403454 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510344 | Pre-made Bovines/Cattle SSTR5/SS5R/SS5-R siRNA oligo Duplex | 510344 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067398 | Pre-made Equine/Horse SSTR5 siRNA oligo Duplex | 100067398 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SSTR5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64830-Ab | Human | Anti-Human SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T64830-Ab | Rat | Anti-Rat SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T64830-Ab | Mouse | Anti-Mouse SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T64830-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T64830-Ab | Cat/Feline | Anti-Cat/Feline SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T64830-Ab | Dog/Canine | Anti-Dog/Canine SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T64830-Ab | Bovines/Cattle | Anti-Bovines/Cattle SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T64830-Ab | Equine/Horse | Anti-Equine/Horse SSTR5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SSTR5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64830-Ag | Human | Human SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64830-Ag | Rat | Rat SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64830-Ag | Mouse | Mouse SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64830-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64830-Ag | Cat/Feline | Cat/Feline SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64830-Ag | Dog/Canine | Dog/Canine SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64830-Ag | Bovines/Cattle | Bovines/Cattle SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64830-Ag | Equine/Horse | Equine/Horse SSTR5 VLP (virus-like particle) | HEK293 | Products Developing |