Explore HRH3/H3R gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T64765
|
| Target Name |
HRH3/H3R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11255
|
| Gene ID |
100058016 (Equus caballus), 105260416 (Felis catus), 11255 (Homo sapiens), 477282 (Canis lupus familiaris)
574253 (Macaca mulatta), 789851 (Bos taurus), 85268 (Rattus norvegicus), 99296 (Mus musculus)
|
| Target Alternative Names |
Eae8,G-protein coupled receptor 97,GPCR97,H3R,HH3R,HRH3,Histamine H3 receptor,Hrh3
|
| Uniprot Accession |
Q9Y5N1,Q9QYN8,P58406
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000008149, ENSG00000101180, ENSCAFG00845016267, ENSMMUG00000050324, ENSBTAG00000031625, ENSMUSG00000039059
|
| Target Classification |
GPCR
|
Pre-made viral vector of HRH3/H3R cDNA Clones/ORF Plasmid
HRH3/H3R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11255 | Pre-made Human HRH3/HH3R/GPCR97 siRNA oligo Duplex | 11255 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo85268 | Pre-made Rat Hrh3 siRNA oligo Duplex | 85268 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo99296 | Pre-made Mouse Hrh3/H3R/Eae8 siRNA oligo Duplex | 99296 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574253 | Pre-made Cynomolgus/Rhesus macaque HRH3 siRNA oligo Duplex | 574253 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo105260416 | Pre-made Cat/Feline HRH3 siRNA oligo Duplex | 105260416 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477282 | Pre-made Dog/Canine HRH3 siRNA oligo Duplex | 477282 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789851 | Pre-made Bovines/Cattle HRH3 siRNA oligo Duplex | 789851 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058016 | Pre-made Equine/Horse HRH3 siRNA oligo Duplex | 100058016 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HRH3/H3R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64765-Ab | Human | Anti-Human HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T64765-Ab | Rat | Anti-Rat HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T64765-Ab | Mouse | Anti-Mouse HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T64765-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T64765-Ab | Cat/Feline | Anti-Cat/Feline HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T64765-Ab | Dog/Canine | Anti-Dog/Canine HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T64765-Ab | Bovines/Cattle | Anti-Bovines/Cattle HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T64765-Ab | Equine/Horse | Anti-Equine/Horse HRH3/H3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HRH3/H3R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64765-Ag | Human | Human HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64765-Ag | Rat | Rat HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64765-Ag | Mouse | Mouse HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64765-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64765-Ag | Cat/Feline | Cat/Feline HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64765-Ag | Dog/Canine | Dog/Canine HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64765-Ag | Bovines/Cattle | Bovines/Cattle HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64765-Ag | Equine/Horse | Equine/Horse HRH3/H3R VLP (virus-like particle) | HEK293 | Products Developing |
