Explore DR6/TNFRSF21/CD358 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013]
| Target ID |
GM-T64744
|
| Target Name |
DR6/TNFRSF21/CD358
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27242
|
| Gene ID |
100068460 (Equus caballus), 101090616 (Felis catus), 27242 (Homo sapiens), 316256 (Rattus norvegicus)
537922 (Bos taurus), 609964 (Canis lupus familiaris), 705101 (Macaca mulatta), 94185 (Mus musculus)
|
| Target Alternative Names |
BM-018,CD358,DR6,Death receptor 6,TNFRSF21,TR7,Tnfrsf21,Tumor necrosis factor receptor superfamily member 21
|
| Uniprot Accession |
O75509,D3ZF92,Q9EPU5
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000017269, ENSG00000146072, ENSBTAG00000020054, ENSCAFG00845013620, ENSMMUG00000011905, ENSMUSG00000023915
|
Pre-made viral vector of DR6/TNFRSF21/CD358 cDNA Clones/ORF Plasmid
DR6/TNFRSF21/CD358 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27242 | Pre-made Human TNFRSF21/DR6/CD358 siRNA oligo Duplex | 27242 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo316256 | Pre-made Rat Tnfrsf21 siRNA oligo Duplex | 316256 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo94185 | Pre-made Mouse Tnfrsf21/DR6/TR7 siRNA oligo Duplex | 94185 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705101 | Pre-made Cynomolgus/Rhesus macaque TNFRSF21 siRNA oligo Duplex | 705101 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090616 | Pre-made Cat/Feline TNFRSF21 siRNA oligo Duplex | 101090616 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609964 | Pre-made Dog/Canine TNFRSF21 siRNA oligo Duplex | 609964 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo537922 | Pre-made Bovines/Cattle TNFRSF21 siRNA oligo Duplex | 537922 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068460 | Pre-made Equine/Horse TNFRSF21 siRNA oligo Duplex | 100068460 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DR6/TNFRSF21/CD358 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64744-Ab | Human | Anti-Human DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T64744-Ab | Rat | Anti-Rat DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T64744-Ab | Mouse | Anti-Mouse DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T64744-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T64744-Ab | Cat/Feline | Anti-Cat/Feline DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T64744-Ab | Dog/Canine | Anti-Dog/Canine DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T64744-Ab | Bovines/Cattle | Anti-Bovines/Cattle DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T64744-Ab | Equine/Horse | Anti-Equine/Horse DR6/TNFRSF21/CD358 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
DR6/TNFRSF21/CD358 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64744-Ag | Human | Human DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64744-Ag | Rat | Rat DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64744-Ag | Mouse | Mouse DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64744-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64744-Ag | Cat/Feline | Cat/Feline DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64744-Ag | Dog/Canine | Dog/Canine DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64744-Ag | Bovines/Cattle | Bovines/Cattle DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64744-Ag | Equine/Horse | Equine/Horse DR6/TNFRSF21/CD358 VLP (virus-like particle) | HEK293 | Products Developing |
