Explore Integrin beta-8/ITGB8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T64597
|
| Target Name |
Integrin beta-8/ITGB8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3696
|
| Gene ID |
100053462 (Equus caballus), 101087724 (Felis catus), 320910 (Mus musculus), 362800 (Rattus norvegicus)
3696 (Homo sapiens), 475253 (Canis lupus familiaris), 536286 (Bos taurus), 707247 (Macaca mulatta)
|
| Target Alternative Names |
ITGB8,Itgb8,4832412O06Rik
|
| Uniprot Accession |
Q0VBD0,P26012
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Regulation of actin cytoskeleton, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000019215, ENSMUSG00000025321, ENSG00000105855, ENSCAFG00845007494, ENSBTAG00000003709, ENSMMUG00000006898
|
| Target Classification |
|
Pre-made viral vector of Integrin beta-8/ITGB8 cDNA Clones/ORF Plasmid
Integrin beta-8/ITGB8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3696 | Pre-made Human ITGB8 siRNA oligo Duplex | 3696 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362800 | Pre-made Rat Itgb8 siRNA oligo Duplex | 362800 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo320910 | Pre-made Mouse Itgb8/4832412O06Rik siRNA oligo Duplex | 320910 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707247 | Pre-made Cynomolgus/Rhesus macaque ITGB8 siRNA oligo Duplex | 707247 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087724 | Pre-made Cat/Feline ITGB8 siRNA oligo Duplex | 101087724 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475253 | Pre-made Dog/Canine ITGB8 siRNA oligo Duplex | 475253 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536286 | Pre-made Bovines/Cattle ITGB8 siRNA oligo Duplex | 536286 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053462 | Pre-made Equine/Horse ITGB8 siRNA oligo Duplex | 100053462 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin beta-8/ITGB8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64597-Ab | Human | Anti-Human Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T64597-Ab | Rat | Anti-Rat Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T64597-Ab | Mouse | Anti-Mouse Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T64597-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T64597-Ab | Cat/Feline | Anti-Cat/Feline Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T64597-Ab | Dog/Canine | Anti-Dog/Canine Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T64597-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T64597-Ab | Equine/Horse | Anti-Equine/Horse Integrin beta-8/ITGB8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Integrin beta-8/ITGB8 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64597-Ag | Human | Human Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64597-Ag | Rat | Rat Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64597-Ag | Mouse | Mouse Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64597-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64597-Ag | Cat/Feline | Cat/Feline Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64597-Ag | Dog/Canine | Dog/Canine Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64597-Ag | Bovines/Cattle | Bovines/Cattle Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64597-Ag | Equine/Horse | Equine/Horse Integrin beta-8/ITGB8 VLP (virus-like particle) | HEK293 | Products Developing |
