Explore HTR3A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T64591
|
| Target Name |
HTR3A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3359
|
| Gene ID |
100009690 (Equus caballus), 101098004 (Felis catus), 15561 (Mus musculus), 3359 (Homo sapiens)
489399 (Canis lupus familiaris), 617674 (Bos taurus), 696912 (Macaca mulatta), 79246 (Rattus norvegicus)
|
| Target Alternative Names |
HTR3A,Htr3a,5-HT3,5-HT3A,5-HT3R,HTR3,5HT3R,5-HT-3,5HT3,Htr3
|
| Uniprot Accession |
P23979,P46098,P35563
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Serotonergic synapse, Taste transduction
|
| Gene Ensembl |
ENSECAG00000020191, ENSMUSG00000032269, ENSG00000166736, ENSCAFG00845000246, ENSBTAG00000010791, ENSMMUG00000007080
|
| Target Classification |
|
Pre-made viral vector of HTR3A cDNA Clones/ORF Plasmid
HTR3A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3359 | Pre-made Human HTR3A/HTR3/5HT3R siRNA oligo Duplex | 3359 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79246 | Pre-made Rat Htr3a/5HT3/Htr3 siRNA oligo Duplex | 79246 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15561 | Pre-made Mouse Htr3a/5-HT3/5-HT3A siRNA oligo Duplex | 15561 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696912 | Pre-made Cynomolgus/Rhesus macaque HTR3A siRNA oligo Duplex | 696912 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098004 | Pre-made Cat/Feline HTR3A siRNA oligo Duplex | 101098004 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489399 | Pre-made Dog/Canine HTR3A siRNA oligo Duplex | 489399 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617674 | Pre-made Bovines/Cattle HTR3A siRNA oligo Duplex | 617674 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009690 | Pre-made Equine/Horse HTR3A siRNA oligo Duplex | 100009690 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTR3A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64591-Ab | Human | Anti-Human HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T64591-Ab | Rat | Anti-Rat HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T64591-Ab | Mouse | Anti-Mouse HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T64591-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T64591-Ab | Cat/Feline | Anti-Cat/Feline HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T64591-Ab | Dog/Canine | Anti-Dog/Canine HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T64591-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T64591-Ab | Equine/Horse | Anti-Equine/Horse HTR3A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HTR3A VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64591-Ag | Human | Human HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64591-Ag | Rat | Rat HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64591-Ag | Mouse | Mouse HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64591-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64591-Ag | Cat/Feline | Cat/Feline HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64591-Ag | Dog/Canine | Dog/Canine HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64591-Ag | Bovines/Cattle | Bovines/Cattle HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64591-Ag | Equine/Horse | Equine/Horse HTR3A VLP (virus-like particle) | HEK293 | Products Developing |
