Explore CA9/CA-IX gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014]
| Target ID |
GM-T64567
|
| Target Name |
CA9/CA-IX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
768
|
| Gene ID |
100055579 (Equus caballus), 101092802 (Felis catus), 230099 (Mus musculus), 313495 (Rattus norvegicus)
511923 (Bos taurus), 611933 (Canis lupus familiaris), 696729 (Macaca mulatta), 768 (Homo sapiens)
|
| Target Alternative Names |
CA-IX,CA9,CAIX,CAIX),Ca9,Car9,Carbonate dehydratase IX,Carbonic anhydrase 9,Carbonic anhydrase IX (CA-IX,MN,MN/CA9,Membrane antigen MN,P54/58N,Renal cell carcinoma-associated antigen G250 (RCC-associated antigen G250),pMW1
|
| Uniprot Accession |
Q8VHB5,Q16790
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, Renal cell carcinoma, Malignant neoplasm of bladder
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000010059, ENSMUSG00000028463, ENSBTAG00000011420, ENSCAFG00845008914, ENSMMUG00000050822, ENSG00000107159
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CA9/CA-IX cDNA Clones/ORF Plasmid
CA9/CA-IX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo768 | Pre-made Human CA9/MN/CAIX siRNA oligo Duplex | 768 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313495 | Pre-made Rat Car9/Ca9 siRNA oligo Duplex | 313495 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo230099 | Pre-made Mouse Car9/Ca9/CAIX siRNA oligo Duplex | 230099 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696729 | Pre-made Cynomolgus/Rhesus macaque CA9 siRNA oligo Duplex | 696729 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092802 | Pre-made Cat/Feline CA9 siRNA oligo Duplex | 101092802 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611933 | Pre-made Dog/Canine CA9 siRNA oligo Duplex | 611933 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511923 | Pre-made Bovines/Cattle CA9 siRNA oligo Duplex | 511923 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055579 | Pre-made Equine/Horse CA9 siRNA oligo Duplex | 100055579 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CA9/CA-IX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64567-Ab | Human | Anti-Human CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T64567-Ab | Rat | Anti-Rat CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T64567-Ab | Mouse | Anti-Mouse CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T64567-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T64567-Ab | Cat/Feline | Anti-Cat/Feline CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T64567-Ab | Dog/Canine | Anti-Dog/Canine CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T64567-Ab | Bovines/Cattle | Anti-Bovines/Cattle CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T64567-Ab | Equine/Horse | Anti-Equine/Horse CA9/CA-IX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CA9/CA-IX VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64567-Ag | Human | Human CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64567-Ag | Rat | Rat CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64567-Ag | Mouse | Mouse CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64567-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64567-Ag | Cat/Feline | Cat/Feline CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64567-Ag | Dog/Canine | Dog/Canine CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64567-Ag | Bovines/Cattle | Bovines/Cattle CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64567-Ag | Equine/Horse | Equine/Horse CA9/CA-IX VLP (virus-like particle) | HEK293 | Products Developing |
