ZAP70/ZAP-70 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

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Target sublocation: Introcelluar Protein.
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Pre-made viral vector of ZAP70/ZAP-70 cDNA Clones/ORF Plasmid

ZAP70/ZAP-70 siRNA/miRNA/oligo for RNA interfence (RNAi)

ZAP70/ZAP-70 antibody/GMab

ZAP70/ZAP-70 recombinant protein