Explore TRPV4 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
| Target ID |
GM-T64213
|
| Target Name |
TRPV4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
59341
|
| Gene ID |
100066552 (Equus caballus), 101084907 (Felis catus), 486308 (Canis lupus familiaris), 540259 (Bos taurus)
59341 (Homo sapiens), 63873 (Mus musculus), 66026 (Rattus norvegicus), 709605 (Macaca mulatta)
|
| Target Alternative Names |
0610033B08Rik,BCYM3,CMT2C,HMSN2C,OTRPC4,Osm-9-like TRP channel 4 (OTRPC4),Otrpc4,SMAL,SPSMA,SSQTL1,TRP12,TRPV4,Transient receptor potential cation channel subfamily V member 4,Transient receptor potential protein 12 (TRP12),Trp12,TrpV4,Trpv4,VR-OAC,VRL-2,VRL2,VROAC,Vanilloid receptor-like channel 2,Vanilloid receptor-like protein 2 (VRL-2),Vanilloid receptor-related osmotically-activated channel (VR-OAC),Vroac
|
| Uniprot Accession |
Q9HBA0,Q9EPK8,Q9ERZ8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Cellular senescence, Inflammatory mediator regulation of TRP channels, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000011734, ENSCAFG00845022016, ENSBTAG00000000031, ENSG00000111199, ENSMUSG00000014158, ENSMMUG00000003942
|
| Target Classification |
Ion Channel
|
Pre-made viral vector of TRPV4 cDNA Clones/ORF Plasmid
TRPV4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo59341 | Pre-made Human TRPV4/SMAL/VRL2 siRNA oligo Duplex | 59341 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo66026 | Pre-made Rat Trpv4/Vroac/Otrpc4 siRNA oligo Duplex | 66026 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo63873 | Pre-made Mouse Trpv4/Trp12/VRL-2 siRNA oligo Duplex | 63873 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709605 | Pre-made Cynomolgus/Rhesus macaque TRPV4 siRNA oligo Duplex | 709605 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084907 | Pre-made Cat/Feline TRPV4 siRNA oligo Duplex | 101084907 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486308 | Pre-made Dog/Canine TRPV4 siRNA oligo Duplex | 486308 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540259 | Pre-made Bovines/Cattle TRPV4 siRNA oligo Duplex | 540259 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066552 | Pre-made Equine/Horse TRPV4 siRNA oligo Duplex | 100066552 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRPV4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T64213-Ab | Human | Anti-Human TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T64213-Ab | Rat | Anti-Rat TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T64213-Ab | Mouse | Anti-Mouse TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T64213-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T64213-Ab | Cat/Feline | Anti-Cat/Feline TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T64213-Ab | Dog/Canine | Anti-Dog/Canine TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T64213-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T64213-Ab | Equine/Horse | Anti-Equine/Horse TRPV4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TRPV4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T64213-Ag | Human | Human TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T64213-Ag | Rat | Rat TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T64213-Ag | Mouse | Mouse TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T64213-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T64213-Ag | Cat/Feline | Cat/Feline TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T64213-Ag | Dog/Canine | Dog/Canine TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T64213-Ag | Bovines/Cattle | Bovines/Cattle TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T64213-Ag | Equine/Horse | Equine/Horse TRPV4 VLP (virus-like particle) | HEK293 | Products Developing |
