Explore IRAK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T63846
|
| Target Name |
IRAK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3654
|
| Gene ID |
100059262 (Equus caballus), 101090500 (Felis catus), 16179 (Mus musculus), 363520 (Rattus norvegicus)
3654 (Homo sapiens), 492247 (Canis lupus familiaris), 533953 (Bos taurus), 699919 (Macaca mulatta)
|
| Target Alternative Names |
IRAK,IRAK-1,IRAK1,IRAK1-S,IRAK1b,Il1rak,Interleukin-1 receptor-associated kinase 1,Irak1,Plpk,RGD1563841,mPLK,pelle
|
| Uniprot Accession |
Q62406,P51617,Q2LGB3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Neurotrophin signaling pathway, Alcoholic liver disease, Pathogenic Escherichia coli infection, Pertussis, Yersinia infection, Leishmaniasis, Chagas disease, Toxoplasmosis, Tuberculosis, Hepatitis B, Measles, Epstein-Barr virus infection, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000009585, ENSMUSG00000031392, ENSG00000184216, ENSCAFG00845027126, ENSBTAG00000016085, ENSMMUG00000018703
|
| Target Classification |
Kinase, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of IRAK1 cDNA Clones/ORF Plasmid
IRAK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3654 | Pre-made Human IRAK1/IRAK/pelle siRNA oligo Duplex | 3654 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363520 | Pre-made Rat Irak1/RGD1563841 siRNA oligo Duplex | 363520 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16179 | Pre-made Mouse Irak1/IRAK/Plpk siRNA oligo Duplex | 16179 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699919 | Pre-made Cynomolgus/Rhesus macaque IRAK1 siRNA oligo Duplex | 699919 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090500 | Pre-made Cat/Feline IRAK1 siRNA oligo Duplex | 101090500 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo492247 | Pre-made Dog/Canine IRAK1 siRNA oligo Duplex | 492247 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533953 | Pre-made Bovines/Cattle IRAK1 siRNA oligo Duplex | 533953 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059262 | Pre-made Equine/Horse IRAK1 siRNA oligo Duplex | 100059262 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IRAK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T63846-Ab | Human | Anti-Human IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T63846-Ab | Rat | Anti-Rat IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T63846-Ab | Mouse | Anti-Mouse IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T63846-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T63846-Ab | Cat/Feline | Anti-Cat/Feline IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T63846-Ab | Dog/Canine | Anti-Dog/Canine IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T63846-Ab | Bovines/Cattle | Anti-Bovines/Cattle IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T63846-Ab | Equine/Horse | Anti-Equine/Horse IRAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
IRAK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T63846-Ag | Human | Human IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T63846-Ag | Rat | Rat IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T63846-Ag | Mouse | Mouse IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T63846-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T63846-Ag | Cat/Feline | Cat/Feline IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T63846-Ag | Dog/Canine | Dog/Canine IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T63846-Ag | Bovines/Cattle | Bovines/Cattle IRAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T63846-Ag | Equine/Horse | Equine/Horse IRAK1 recombinant protein | Mammalian cell | Detail |
