Explore HDAC4 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T63816
|
| Target Name |
HDAC4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9759
|
| Gene ID |
100067014 (Equus caballus), 101093384 (Felis catus), 208727 (Mus musculus), 363287 (Rattus norvegicus)
517559 (Bos taurus), 607662 (Canis lupus familiaris), 710797 (Macaca mulatta), 9759 (Homo sapiens)
|
| Target Alternative Names |
4932408F19Rik,AHO3,BDMR,HA6116,HD4,HDAC-4,HDAC-A,HDAC4,HDACA,Hdac4,Histone deacetylase 4,NEDCHF,NEDCHID
|
| Uniprot Accession |
Q6NZM9,Q99P99,P56524
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000017406, ENSMUSG00000026313, ENSBTAG00000017764, ENSCAFG00845030282, ENSMMUG00000006077, ENSG00000068024
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HDAC4 cDNA Clones/ORF Plasmid
HDAC4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9759 | Pre-made Human HDAC4/HD4/AHO3 siRNA oligo Duplex | 9759 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363287 | Pre-made Rat Hdac4 siRNA oligo Duplex | 363287 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo208727 | Pre-made Mouse Hdac4/HD4/4932408F19Rik siRNA oligo Duplex | 208727 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710797 | Pre-made Cynomolgus/Rhesus macaque HDAC4 siRNA oligo Duplex | 710797 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093384 | Pre-made Cat/Feline HDAC4 siRNA oligo Duplex | 101093384 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607662 | Pre-made Dog/Canine HDAC4 siRNA oligo Duplex | 607662 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517559 | Pre-made Bovines/Cattle HDAC4 siRNA oligo Duplex | 517559 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067014 | Pre-made Equine/Horse HDAC4 siRNA oligo Duplex | 100067014 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HDAC4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T63816-Ab | Human | Anti-Human HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T63816-Ab | Rat | Anti-Rat HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T63816-Ab | Mouse | Anti-Mouse HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T63816-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T63816-Ab | Cat/Feline | Anti-Cat/Feline HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T63816-Ab | Dog/Canine | Anti-Dog/Canine HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T63816-Ab | Bovines/Cattle | Anti-Bovines/Cattle HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T63816-Ab | Equine/Horse | Anti-Equine/Horse HDAC4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HDAC4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T63816-Ag | Human | Human HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T63816-Ag | Rat | Rat HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T63816-Ag | Mouse | Mouse HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T63816-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T63816-Ag | Cat/Feline | Cat/Feline HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T63816-Ag | Dog/Canine | Dog/Canine HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T63816-Ag | Bovines/Cattle | Bovines/Cattle HDAC4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T63816-Ag | Equine/Horse | Equine/Horse HDAC4 recombinant protein | Mammalian cell | Detail |
