Explore FIGF/VEGFD gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]
| Target ID |
GM-T63803
|
| Target Name |
FIGF/VEGFD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2277
|
| Gene ID |
100050877 (Equus caballus), 14205 (Mus musculus), 2277 (Homo sapiens), 286799 (Bos taurus)
360457 (Rattus norvegicus), 491749 (Canis lupus familiaris), 493703 (Felis catus), 712654 (Macaca mulatta)
|
| Target Alternative Names |
FIGF,Figf,VEGF-D,VEGFD,Vascular endothelial growth factor D,Vegf-d,Vegfd,c-Fos-induced growth factor (FIGF)
|
| Uniprot Accession |
P97946,O43915,O35251
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
Breast Cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, TNF signaling pathway, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000011948, ENSMUSG00000031380, ENSG00000165197, ENSBTAG00000009476, ENSCAFG00845029554, ENSMMUG00000015738
|
Pre-made viral vector of FIGF/VEGFD cDNA Clones/ORF Plasmid
FIGF/VEGFD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2277 | Pre-made Human VEGFD/FIGF/VEGF-D siRNA oligo Duplex | 2277 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360457 | Pre-made Rat Vegfd/Figf/Vegf-d siRNA oligo Duplex | 360457 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14205 | Pre-made Mouse Vegfd/Figf/VEGF-D siRNA oligo Duplex | 14205 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712654 | Pre-made Cynomolgus/Rhesus macaque VEGFD siRNA oligo Duplex | 712654 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493703 | Pre-made Cat/Feline VEGFD siRNA oligo Duplex | 493703 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491749 | Pre-made Dog/Canine VEGFD siRNA oligo Duplex | 491749 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286799 | Pre-made Bovines/Cattle VEGFD/FIGF/VEGF-D siRNA oligo Duplex | 286799 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050877 | Pre-made Equine/Horse VEGFD siRNA oligo Duplex | 100050877 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FIGF/VEGFD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T63803-Ab | Human | Anti-Human FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T63803-Ab | Rat | Anti-Rat FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T63803-Ab | Mouse | Anti-Mouse FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T63803-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T63803-Ab | Cat/Feline | Anti-Cat/Feline FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T63803-Ab | Dog/Canine | Anti-Dog/Canine FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T63803-Ab | Bovines/Cattle | Anti-Bovines/Cattle FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T63803-Ab | Equine/Horse | Anti-Equine/Horse FIGF/VEGFD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
FIGF/VEGFD recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T63803-Ag | Human | Human FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T63803-Ag | Rat | Rat FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T63803-Ag | Mouse | Mouse FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T63803-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T63803-Ag | Cat/Feline | Cat/Feline FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T63803-Ag | Dog/Canine | Dog/Canine FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T63803-Ag | Bovines/Cattle | Bovines/Cattle FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T63803-Ag | Equine/Horse | Equine/Horse FIGF/VEGFD recombinant protein | Mammalian cell | Detail |
