Explore ENPP2/E-NPP2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
| Target ID |
GM-T63512
|
| Target Name |
ENPP2/E-NPP2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5168
|
| Gene ID |
100057101 (Equus caballus), 101097620 (Felis catus), 18606 (Mus musculus), 482026 (Canis lupus familiaris)
5168 (Homo sapiens), 532663 (Bos taurus), 705287 (Macaca mulatta), 84050 (Rattus norvegicus)
|
| Target Alternative Names |
ATX,ATX-X,AUTOTAXIN,Autotaxin,E-NPP 2,E-NPP2,ENPP2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2),Enpp2,Extracellular lysophospholipase D (LysoPLD),LysoPLD,NPP2,Npps2,PD-IALPHA,PD-Ialpha,PDNP2,Pdnp2,lysoPLD
|
| Uniprot Accession |
Q9R1E6,Q13822,A1A4K5,Q64610
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Ether lipid metabolism
|
| Gene Ensembl |
ENSECAG00000003776, ENSMUSG00000022425, ENSCAFG00845005953, ENSG00000136960, ENSBTAG00000013165, ENSMMUG00000004903
|
Pre-made viral vector of ENPP2/E-NPP2 cDNA Clones/ORF Plasmid
ENPP2/E-NPP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5168 | Pre-made Human ENPP2/ATX/NPP2 siRNA oligo Duplex | 5168 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84050 | Pre-made Rat Enpp2 siRNA oligo Duplex | 84050 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18606 | Pre-made Mouse Enpp2/ATX/Npps2 siRNA oligo Duplex | 18606 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705287 | Pre-made Cynomolgus/Rhesus macaque ENPP2 siRNA oligo Duplex | 705287 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097620 | Pre-made Cat/Feline ENPP2 siRNA oligo Duplex | 101097620 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482026 | Pre-made Dog/Canine ENPP2 siRNA oligo Duplex | 482026 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532663 | Pre-made Bovines/Cattle ENPP2 siRNA oligo Duplex | 532663 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057101 | Pre-made Equine/Horse ENPP2 siRNA oligo Duplex | 100057101 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ENPP2/E-NPP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T63512-Ab | Human | Anti-Human ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T63512-Ab | Rat | Anti-Rat ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T63512-Ab | Mouse | Anti-Mouse ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T63512-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T63512-Ab | Cat/Feline | Anti-Cat/Feline ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T63512-Ab | Dog/Canine | Anti-Dog/Canine ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T63512-Ab | Bovines/Cattle | Anti-Bovines/Cattle ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T63512-Ab | Equine/Horse | Anti-Equine/Horse ENPP2/E-NPP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ENPP2/E-NPP2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T63512-Ag | Human | Human ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T63512-Ag | Rat | Rat ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T63512-Ag | Mouse | Mouse ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T63512-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T63512-Ag | Cat/Feline | Cat/Feline ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T63512-Ag | Dog/Canine | Dog/Canine ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T63512-Ag | Bovines/Cattle | Bovines/Cattle ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T63512-Ag | Equine/Horse | Equine/Horse ENPP2/E-NPP2 VLP (virus-like particle) | HEK293 | Products Developing |
