Explore PAR2/F2RL1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]
| Target ID |
GM-T62841
|
| Target Name |
PAR2/F2RL1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2150
|
| Gene ID |
100073277 (Equus caballus), 101082879 (Felis catus), 116677 (Rattus norvegicus), 14063 (Mus musculus)
2150 (Homo sapiens), 488940 (Canis lupus familiaris), 526525 (Bos taurus), 707479 (Macaca mulatta)
|
| Target Alternative Names |
Coagulation factor II receptor-like 1,F2RL1,F2rl1,G-protein coupled receptor 11,GPR11,Gpcr11,PAR-2,PAR2,Par-2,Par2,Proteinase-activated receptor 2,Thrombin receptor-like 1
|
| Uniprot Accession |
Q63645,P55086,P55085,Q2HJA4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels, African trypanosomiasis
|
| Gene Ensembl |
ENSECAG00000002867, ENSMUSG00000021678, ENSG00000164251, ENSCAFG00845010229, ENSBTAG00000034848, ENSMMUG00000060389
|
| Target Classification |
GPCR, Kinase
|
Pre-made viral vector of PAR2/F2RL1 cDNA Clones/ORF Plasmid
PAR2/F2RL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2150 | Pre-made Human F2RL1/PAR2/GPR11 siRNA oligo Duplex | 2150 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116677 | Pre-made Rat F2rl1/Par2/Par-2 siRNA oligo Duplex | 116677 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14063 | Pre-made Mouse F2rl1/Par2/PAR-2 siRNA oligo Duplex | 14063 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707479 | Pre-made Cynomolgus/Rhesus macaque F2RL1 siRNA oligo Duplex | 707479 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082879 | Pre-made Cat/Feline F2RL1 siRNA oligo Duplex | 101082879 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488940 | Pre-made Dog/Canine F2RL1 siRNA oligo Duplex | 488940 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526525 | Pre-made Bovines/Cattle F2RL1/PAR2 siRNA oligo Duplex | 526525 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073277 | Pre-made Equine/Horse F2RL1/PAR2 siRNA oligo Duplex | 100073277 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PAR2/F2RL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T62841-Ab | Human | Anti-Human PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T62841-Ab | Rat | Anti-Rat PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T62841-Ab | Mouse | Anti-Mouse PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T62841-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T62841-Ab | Cat/Feline | Anti-Cat/Feline PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T62841-Ab | Dog/Canine | Anti-Dog/Canine PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T62841-Ab | Bovines/Cattle | Anti-Bovines/Cattle PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T62841-Ab | Equine/Horse | Anti-Equine/Horse PAR2/F2RL1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PAR2/F2RL1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T62841-Ag | Human | Human PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T62841-Ag | Rat | Rat PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T62841-Ag | Mouse | Mouse PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T62841-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T62841-Ag | Cat/Feline | Cat/Feline PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T62841-Ag | Dog/Canine | Dog/Canine PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T62841-Ag | Bovines/Cattle | Bovines/Cattle PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T62841-Ag | Equine/Horse | Equine/Horse PAR2/F2RL1 VLP (virus-like particle) | HEK293 | Products Developing |
