Explore SYK gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
| Target ID |
GM-T62431
|
| Target Name |
SYK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6850
|
| Gene ID |
100063383 (Equus caballus), 101087013 (Felis catus), 20963 (Mus musculus), 25155 (Rattus norvegicus)
484196 (Canis lupus familiaris), 515515 (Bos taurus), 6850 (Homo sapiens), 704102 (Macaca mulatta)
|
| Target Alternative Names |
IMD82,SYK,Spleen tyrosine kinase,Syk,Sykb,Tyrosine-protein kinase SYK,p72-Syk,p72syk
|
| Uniprot Accession |
P48025,Q64725,P43405
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NF-kappa B signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Osteoclast differentiation, Platelet activation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000009488, ENSMUSG00000021457, ENSCAFG00845018106, ENSBTAG00000004767, ENSG00000165025, ENSMMUG00000001748
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of SYK cDNA Clones/ORF Plasmid
SYK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6850 | Pre-made Human SYK/IMD82/p72-Syk siRNA oligo Duplex | 6850 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25155 | Pre-made Rat Syk/p72syk siRNA oligo Duplex | 25155 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20963 | Pre-made Mouse Syk/Sykb siRNA oligo Duplex | 20963 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704102 | Pre-made Cynomolgus/Rhesus macaque SYK siRNA oligo Duplex | 704102 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087013 | Pre-made Cat/Feline SYK siRNA oligo Duplex | 101087013 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484196 | Pre-made Dog/Canine SYK siRNA oligo Duplex | 484196 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515515 | Pre-made Bovines/Cattle SYK siRNA oligo Duplex | 515515 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063383 | Pre-made Equine/Horse SYK siRNA oligo Duplex | 100063383 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SYK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T62431-Ab | Human | Anti-Human SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T62431-Ab | Rat | Anti-Rat SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T62431-Ab | Mouse | Anti-Mouse SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T62431-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T62431-Ab | Cat/Feline | Anti-Cat/Feline SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T62431-Ab | Dog/Canine | Anti-Dog/Canine SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T62431-Ab | Bovines/Cattle | Anti-Bovines/Cattle SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T62431-Ab | Equine/Horse | Anti-Equine/Horse SYK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SYK VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T62431-Ag | Human | Human SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T62431-Ag | Rat | Rat SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T62431-Ag | Mouse | Mouse SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T62431-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T62431-Ag | Cat/Feline | Cat/Feline SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T62431-Ag | Dog/Canine | Dog/Canine SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T62431-Ag | Bovines/Cattle | Bovines/Cattle SYK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T62431-Ag | Equine/Horse | Equine/Horse SYK VLP (virus-like particle) | HEK293 | Products Developing |
