TH Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore TH gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Target ID	GM-T62390
Target Name	TH
Gene Group ldentifer （Target Gene ID in Homo species)	7054
Gene ID	100146648 (Equus caballus), 101090720 (Felis catus), 21823 (Mus musculus), 25085 (Rattus norvegicus) 280707 (Bos taurus), 403444 (Canis lupus familiaris), 7054 (Homo sapiens), 721137 (Macaca mulatta)
Target Alternative Names	DYT14,DYT5b,TH,TYH,Th,The,Tyrosine 3-hydroxylase (TH),Tyrosine 3-monooxygenase
Uniprot Accession	P24529,P04177,P17289,Q76IQ3,P07101
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease from KEGG	Metabolic pathways, Prolactin signaling pathway, Cocaine addiction, Amphetamine addiction
Gene Ensembl	ENSECAG00000024625, ENSMUSG00000000214, ENSBTAG00000026768, ENSCAFG00845011201, ENSG00000180176, ENSMMUG00000003912

Pre-made viral vector of TH cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLV001783	Human TH/DYT14/DYT5b Lentivirus plasmid	NM_199292	7054	Human	Lentivirus plasmid	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMPC001247	Human TH/DYT14/DYT5b Mammalian (Non-Viral Vector) plasmid	NM_199292.3	7054	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV001783	Human TH/DYT14/DYT5b Lentivirus particle	NM_199292	7054	Human	Lentivirus particle	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMLPm002973	Mouse Th Lentivirus plasmid	NM_009377	21823	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm002973	Mouse Th Lentivirus particle	NM_009377	21823	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

TH siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo7054	Pre-made Human TH/TYH/DYT14 siRNA oligo Duplex	7054	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo25085	Pre-made Rat Th/The siRNA oligo Duplex	25085	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo21823	Pre-made Mouse Th siRNA oligo Duplex	21823	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo721137	Pre-made Cynomolgus/Rhesus macaque TH siRNA oligo Duplex	721137	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101090720	Pre-made Cat/Feline TH siRNA oligo Duplex	101090720	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo403444	Pre-made Dog/Canine TH siRNA oligo Duplex	403444	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo280707	Pre-made Bovines/Cattle TH siRNA oligo Duplex	280707	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100146648	Pre-made Equine/Horse TH siRNA oligo Duplex	100146648	Equine/Horse	In-vitro grade; in-vivo grade	Detail

TH antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T62390-Ab	Human	Anti-Human TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-T62390-Ab	Rat	Anti-Rat TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-T62390-Ab	Mouse	Anti-Mouse TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-T62390-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-T62390-Ab	Cat/Feline	Anti-Cat/Feline TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-T62390-Ab	Dog/Canine	Anti-Dog/Canine TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-T62390-Ab	Bovines/Cattle	Anti-Bovines/Cattle TH monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-T62390-Ab	Equine/Horse	Anti-Equine/Horse TH monoclonal antibody	mab	Therapeutics Target antibody	Detail

TH recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T62390-Ag	Human	Human TH recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T62390-Ag	Rat	Rat TH recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T62390-Ag	Mouse	Mouse TH recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T62390-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque TH recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T62390-Ag	Cat/Feline	Cat/Feline TH recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T62390-Ag	Dog/Canine	Dog/Canine TH recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T62390-Ag	Bovines/Cattle	Bovines/Cattle TH recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T62390-Ag	Equine/Horse	Equine/Horse TH recombinant protein	Mammalian cell	Detail