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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a motilin receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]
| Target ID |
GM-T62306
|
| Target Name |
MLNR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2862
|
| Gene ID |
101100612 (Felis catus), 106781886 (Equus caballus), 2862 (Homo sapiens), 608252 (Canis lupus familiaris)
705803 (Macaca mulatta), 788867 (Bos taurus)
|
| Target Alternative Names |
G-protein coupled receptor 38,GPR38,MLNR,MTLR1,Motilin receptor
|
| Uniprot Accession |
O43193
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000035160, ENSG00000102539, ENSCAFG00845024409, ENSMMUG00000056827, ENSBTAG00000010475
|
| Target Classification |
GPCR
|
MLNR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2862 | Pre-made Human MLNR/GPR38/MTLR1 siRNA oligo Duplex | 2862 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705803 | Pre-made Cynomolgus/Rhesus macaque MLNR siRNA oligo Duplex | 705803 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100612 | Pre-made Cat/Feline MLNR siRNA oligo Duplex | 101100612 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608252 | Pre-made Dog/Canine MLNR siRNA oligo Duplex | 608252 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo788867 | Pre-made Bovines/Cattle MLNR siRNA oligo Duplex | 788867 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106781886 | Pre-made Equine/Horse MLNR siRNA oligo Duplex | 106781886 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MLNR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T62306-Ab | Human | Anti-Human MLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T62306-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T62306-Ab | Cat/Feline | Anti-Cat/Feline MLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T62306-Ab | Dog/Canine | Anti-Dog/Canine MLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T62306-Ab | Bovines/Cattle | Anti-Bovines/Cattle MLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T62306-Ab | Equine/Horse | Anti-Equine/Horse MLNR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MLNR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T62306-Ag | Human | Human MLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T62306-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T62306-Ag | Cat/Feline | Cat/Feline MLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T62306-Ag | Dog/Canine | Dog/Canine MLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T62306-Ag | Bovines/Cattle | Bovines/Cattle MLNR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T62306-Ag | Equine/Horse | Equine/Horse MLNR VLP (virus-like particle) | HEK293 | Products Developing |
