Explore NMDAR1/GRIN1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T62276
|
| Target Name |
NMDAR1/GRIN1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2902
|
| Gene ID |
100059861 (Equus caballus), 100336579 (Bos taurus), 101082021 (Felis catus), 14810 (Mus musculus)
24408 (Rattus norvegicus), 2902 (Homo sapiens), 494007 (Canis lupus familiaris), 574380 (Macaca mulatta)
|
| Target Alternative Names |
GRIN1,Grin1,NR1,GluN1,Nmdar,NMD-R1,NMDAR1,M100174,Rgsc174,GluRzeta1,GluRdelta1,MRD8,hNR1,NMDA1,DEE101,NDHMSD,NDHMSR
|
| Uniprot Accession |
P35438,P35439,Q05586,Q5R1P0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Cocaine addiction, Amphetamine addiction, Nicotine addiction
|
| Gene Ensembl |
ENSECAG00000024535, ENSBTAG00000047202, ENSMUSG00000026959, ENSG00000176884, ENSCAFG00845024581, ENSMMUG00000001661
|
| Target Classification |
|
Pre-made viral vector of NMDAR1/GRIN1 cDNA Clones/ORF Plasmid
NMDAR1/GRIN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2902 | Pre-made Human GRIN1/NR1/MRD8 siRNA oligo Duplex | 2902 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24408 | Pre-made Rat Grin1/NR1/GluN1 siRNA oligo Duplex | 24408 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14810 | Pre-made Mouse Grin1/NR1/GluN1 siRNA oligo Duplex | 14810 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574380 | Pre-made Cynomolgus/Rhesus macaque GRIN1 siRNA oligo Duplex | 574380 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082021 | Pre-made Cat/Feline GRIN1 siRNA oligo Duplex | 101082021 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo494007 | Pre-made Dog/Canine GRIN1/NR1/GluN1 siRNA oligo Duplex | 494007 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336579 | Pre-made Bovines/Cattle GRIN1 siRNA oligo Duplex | 100336579 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059861 | Pre-made Equine/Horse GRIN1 siRNA oligo Duplex | 100059861 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NMDAR1/GRIN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T62276-Ab | Human | Anti-Human NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T62276-Ab | Rat | Anti-Rat NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T62276-Ab | Mouse | Anti-Mouse NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T62276-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T62276-Ab | Cat/Feline | Anti-Cat/Feline NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T62276-Ab | Dog/Canine | Anti-Dog/Canine NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T62276-Ab | Bovines/Cattle | Anti-Bovines/Cattle NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T62276-Ab | Equine/Horse | Anti-Equine/Horse NMDAR1/GRIN1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NMDAR1/GRIN1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T62276-Ag | Human | Human NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T62276-Ag | Rat | Rat NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T62276-Ag | Mouse | Mouse NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T62276-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T62276-Ag | Cat/Feline | Cat/Feline NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T62276-Ag | Dog/Canine | Dog/Canine NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T62276-Ag | Bovines/Cattle | Bovines/Cattle NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T62276-Ag | Equine/Horse | Equine/Horse NMDAR1/GRIN1 VLP (virus-like particle) | HEK293 | Products Developing |
