DOPA decarboxylase/DDC Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore DOPA decarboxylase/DDC gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

Target ID GM-T62193
Target Name DOPA decarboxylase/DDC
Gene Group ldentifer
（Target Gene ID in Homo species) 		1644
Gene ID 100052557 (Equus caballus), 101082989 (Felis catus), 13195 (Mus musculus), 1644 (Homo sapiens)
24311 (Rattus norvegicus), 280762 (Bos taurus), 606852 (Canis lupus familiaris), 693677 (Macaca mulatta)
Target Alternative Names AADC,Aadc,Aromatic-L-amino-acid decarboxylase,DDC,DOPA decarboxylase,DOPA decarboxylase (DDC),Ddc
Uniprot Accession O88533,P20711,P14173,P27718
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG Metabolic pathways, Serotonergic synapse, Cocaine addiction, Amphetamine addiction
Gene Ensembl ENSECAG00000009450, ENSMUSG00000020182, ENSG00000132437, ENSBTAG00000020869, ENSCAFG00845010355, ENSMMUG00000019991


Pre-made viral vector of DOPA decarboxylase/DDC cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV001784Human DDC/AADC Lentivirus plasmidNM_0010829711644HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000892Human DDC/AADC Mammalian (Non-Viral Vector) plasmidNM_0010829711644HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLV001784Human DDC/AADC Lentivirus particleNM_0010829711644HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001297Mouse Ddc/Aadc Adeno-associate virus(AAV) plasmidNM_016672.413195MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm001636Mouse Ddc/Aadc Lentivirus plasmidNM_01667213195MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001297Mouse Ddc/Aadc Adeno-associate virus(AAV) particleNM_016672.413195MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm001636Mouse Ddc/Aadc Lentivirus particleNM_01667213195MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


DOPA decarboxylase/DDC siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo1644Pre-made Human DDC/AADC siRNA oligo Duplex1644HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24311Pre-made Rat Ddc/AADC siRNA oligo Duplex24311RatIn-vitro grade; in-vivo gradeDetail
pGMoligo13195Pre-made Mouse Ddc/Aadc siRNA oligo Duplex13195MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo693677Pre-made Cynomolgus/Rhesus macaque DDC siRNA oligo Duplex693677Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101082989Pre-made Cat/Feline DDC siRNA oligo Duplex101082989Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo606852Pre-made Dog/Canine DDC siRNA oligo Duplex606852Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo280762Pre-made Bovines/Cattle DDC siRNA oligo Duplex280762Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100052557Pre-made Equine/Horse DDC siRNA oligo Duplex100052557Equine/HorseIn-vitro grade; in-vivo gradeDetail


DOPA decarboxylase/DDC antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T62193-AbHumanAnti-Human DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T62193-AbRatAnti-Rat DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T62193-AbMouseAnti-Mouse DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T62193-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T62193-AbCat/FelineAnti-Cat/Feline DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T62193-AbDog/CanineAnti-Dog/Canine DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T62193-AbBovines/CattleAnti-Bovines/Cattle DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T62193-AbEquine/HorseAnti-Equine/Horse DOPA decarboxylase/DDC monoclonal antibodymabTherapeutics Target antibodyDetail


DOPA decarboxylase/DDC recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T62193-AgHumanHuman DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-rg-T62193-AgRatRat DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-mg-T62193-AgMouseMouse DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-cynog-T62193-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-felg-T62193-AgCat/FelineCat/Feline DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-cang-T62193-AgDog/CanineDog/Canine DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-bovg-T62193-AgBovines/CattleBovines/Cattle DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail
GM-Tg-equg-T62193-AgEquine/HorseEquine/Horse DOPA decarboxylase/DDC recombinant proteinMammalian cellDetail