Explore SP1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
| Target ID |
GM-T61544
|
| Target Name |
SP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6667
|
| Gene ID |
100629527 (Equus caballus), 101100227 (Felis catus), 20683 (Mus musculus), 24790 (Rattus norvegicus)
486507 (Canis lupus familiaris), 540741 (Bos taurus), 6667 (Homo sapiens), 702710 (Macaca mulatta)
|
| Target Alternative Names |
1110003E12Rik,SP1,Sp1,Sp1-1,Transcription factor Sp1
|
| Uniprot Accession |
O89090,Q01714,P08047
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
gastric cancer
|
| Disease from KEGG |
Endocrine resistance, TGF-beta signaling pathway, Cortisol synthesis and secretion, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Human cytomegalovirus infection, Pathways in cancer, Breast cancer, Choline metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000028970, ENSMUSG00000001280, ENSCAFG00845019670, ENSBTAG00000003021, ENSG00000185591, ENSMMUG00000020036
|
Pre-made viral vector of SP1 cDNA Clones/ORF Plasmid
SP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6667 | Pre-made Human SP1 siRNA oligo Duplex | 6667 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24790 | Pre-made Rat Sp1 siRNA oligo Duplex | 24790 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20683 | Pre-made Mouse Sp1/Sp1-1/1110003E12Rik siRNA oligo Duplex | 20683 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702710 | Pre-made Cynomolgus/Rhesus macaque SP1 siRNA oligo Duplex | 702710 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100227 | Pre-made Cat/Feline SP1 siRNA oligo Duplex | 101100227 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486507 | Pre-made Dog/Canine SP1 siRNA oligo Duplex | 486507 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540741 | Pre-made Bovines/Cattle SP1 siRNA oligo Duplex | 540741 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100629527 | Pre-made Equine/Horse SP1 siRNA oligo Duplex | 100629527 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T61544-Ab | Human | Anti-Human SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T61544-Ab | Rat | Anti-Rat SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T61544-Ab | Mouse | Anti-Mouse SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T61544-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T61544-Ab | Cat/Feline | Anti-Cat/Feline SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T61544-Ab | Dog/Canine | Anti-Dog/Canine SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T61544-Ab | Bovines/Cattle | Anti-Bovines/Cattle SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T61544-Ab | Equine/Horse | Anti-Equine/Horse SP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
SP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T61544-Ag | Human | Human SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T61544-Ag | Rat | Rat SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T61544-Ag | Mouse | Mouse SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T61544-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T61544-Ag | Cat/Feline | Cat/Feline SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T61544-Ag | Dog/Canine | Dog/Canine SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T61544-Ag | Bovines/Cattle | Bovines/Cattle SP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T61544-Ag | Equine/Horse | Equine/Horse SP1 recombinant protein | Mammalian cell | Detail |
