Explore ITPR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
| Target ID |
GM-T61227
|
| Target Name |
ITPR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3708
|
| Gene ID |
100052808 (Equus caballus), 101100546 (Felis catus), 16438 (Mus musculus), 25262 (Rattus norvegicus)
317697 (Bos taurus), 3708 (Homo sapiens), 476548 (Canis lupus familiaris), 703669 (Macaca mulatta)
|
| Target Alternative Names |
4,5 trisphosphate receptor,5-trisphosphate receptor (Type 1 InsP3 receptor),5-trisphosphate receptor type 1,5-trisphosphate-gated calcium channel ITPR1,ACV,CLA4,D6Pas2,Gm10429,I145TR,INSP3R1,IP3 receptor isoform 1 (IP3R 1,IP3R,IP3R 1,IP3R1,ITPR1,Inositol 1,InsP3R,InsP3R1,InsP3R1),Ip3r,Itpr-1,Itpr1,P400,PPP1R94,Pcp-1,Pcp1,SCA15,SCA16,SCA29,Type 1 inositol 1,insP3R1,opt,wblo
|
| Uniprot Accession |
P11881,P29994,Q9TU34,Q14643
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, Gap junction, Platelet activation, NOD-like receptor signaling pathway, C-type lectin receptor signaling pathway, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, Inflammatory mediator regulation of TRP channels, GnRH signaling pathway, Thyroid hormone synthesis, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Proteoglycans in cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000020933, ENSMUSG00000030102, ENSBTAG00000020455, ENSG00000150995, ENSCAFG00845011583, ENSMMUG00000012574
|
ITPR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3708 | Pre-made Human ITPR1/ACV/CLA4 siRNA oligo Duplex | 3708 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25262 | Pre-made Rat Itpr1/P400/IP3R1 siRNA oligo Duplex | 25262 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16438 | Pre-made Mouse Itpr1/opt/Ip3r siRNA oligo Duplex | 16438 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703669 | Pre-made Cynomolgus/Rhesus macaque ITPR1 siRNA oligo Duplex | 703669 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100546 | Pre-made Cat/Feline ITPR1 siRNA oligo Duplex | 101100546 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476548 | Pre-made Dog/Canine ITPR1 siRNA oligo Duplex | 476548 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317697 | Pre-made Bovines/Cattle ITPR1 siRNA oligo Duplex | 317697 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052808 | Pre-made Equine/Horse ITPR1 siRNA oligo Duplex | 100052808 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ITPR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T61227-Ab | Human | Anti-Human ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T61227-Ab | Rat | Anti-Rat ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T61227-Ab | Mouse | Anti-Mouse ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T61227-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T61227-Ab | Cat/Feline | Anti-Cat/Feline ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T61227-Ab | Dog/Canine | Anti-Dog/Canine ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T61227-Ab | Bovines/Cattle | Anti-Bovines/Cattle ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T61227-Ab | Equine/Horse | Anti-Equine/Horse ITPR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ITPR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T61227-Ag | Human | Human ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T61227-Ag | Rat | Rat ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T61227-Ag | Mouse | Mouse ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T61227-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T61227-Ag | Cat/Feline | Cat/Feline ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T61227-Ag | Dog/Canine | Dog/Canine ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T61227-Ag | Bovines/Cattle | Bovines/Cattle ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T61227-Ag | Equine/Horse | Equine/Horse ITPR1 VLP (virus-like particle) | HEK293 | Products Developing |
