Explore CNTFR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
| Target ID |
GM-T61033
|
| Target Name |
CNTFR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1271
|
| Gene ID |
100146590 (Equus caballus), 101083719 (Felis catus), 1271 (Homo sapiens), 12804 (Mus musculus)
313173 (Rattus norvegicus), 442941 (Canis lupus familiaris), 539548 (Bos taurus), 700959 (Macaca mulatta)
|
| Target Alternative Names |
CNTF receptor subunit alpha,CNTFR,CNTFR-alpha,CNTFRALPHA,Ciliary neurotrophic factor receptor subunit alpha,Cntfr,Cntfralpha
|
| Uniprot Accession |
P26992,O88507,Q08406,Q71DR4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSECAG00000006176, ENSG00000122756, ENSMUSG00000028444, ENSCAFG00845024273, ENSBTAG00000015361, ENSMMUG00000020780
|
Pre-made viral vector of CNTFR cDNA Clones/ORF Plasmid
CNTFR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1271 | Pre-made Human CNTFR siRNA oligo Duplex | 1271 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313173 | Pre-made Rat Cntfr/CNTFR-alpha siRNA oligo Duplex | 313173 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12804 | Pre-made Mouse Cntfr/Cntfralpha siRNA oligo Duplex | 12804 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700959 | Pre-made Cynomolgus/Rhesus macaque CNTFR siRNA oligo Duplex | 700959 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083719 | Pre-made Cat/Feline CNTFR siRNA oligo Duplex | 101083719 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442941 | Pre-made Dog/Canine CNTFR/CNTFRALPHA siRNA oligo Duplex | 442941 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539548 | Pre-made Bovines/Cattle CNTFR siRNA oligo Duplex | 539548 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146590 | Pre-made Equine/Horse CNTFR siRNA oligo Duplex | 100146590 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CNTFR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T61033-Ab | Human | Anti-Human CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T61033-Ab | Rat | Anti-Rat CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T61033-Ab | Mouse | Anti-Mouse CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T61033-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T61033-Ab | Cat/Feline | Anti-Cat/Feline CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T61033-Ab | Dog/Canine | Anti-Dog/Canine CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T61033-Ab | Bovines/Cattle | Anti-Bovines/Cattle CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T61033-Ab | Equine/Horse | Anti-Equine/Horse CNTFR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CNTFR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T61033-Ag | Human | Human CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T61033-Ag | Rat | Rat CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T61033-Ag | Mouse | Mouse CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T61033-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T61033-Ag | Cat/Feline | Cat/Feline CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T61033-Ag | Dog/Canine | Dog/Canine CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T61033-Ag | Bovines/Cattle | Bovines/Cattle CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T61033-Ag | Equine/Horse | Equine/Horse CNTFR VLP (virus-like particle) | HEK293 | Products Developing |
