HCRT Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore HCRT gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]

Target ID	GM-T60744
Target Name	HCRT
Gene Group ldentifer （Target Gene ID in Homo species)	3060
Gene ID	100066236 (Equus caballus), 111557774 (Felis catus), 15171 (Mus musculus), 25723 (Rattus norvegicus) 281222 (Bos taurus), 3060 (Homo sapiens), 607641 (Canis lupus familiaris), 709564 (Macaca mulatta)
Target Alternative Names	HCRT,Hcrt,Hypocretin (Hcrt),Hypocretin neuropeptide precursor,NRCLP1,OX,Orexin precursor,PPOX,Prepro-orexin,Preprohypocretin,orexin-A
Uniprot Accession	O55241,O55232,P56717,O43612,Q9GLF6
Protein Sub-location	Secreted Protein/Potential Cytokines
Category	Therapeutics Target
Disease from KEGG	Neuroactive ligand-receptor interaction
Gene Ensembl	ENSECAG00000001687, ENSMUSG00000045471, ENSBTAG00000000665, ENSG00000161610, ENSCAFG00845010112, ENSMMUG00000006406

Pre-made viral vector of HCRT cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP001015	Human HCRT/NRCLP1/OX Lentivirus plasmid	NM_001524	3060	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP001015	Human HCRT/NRCLP1/OX Lentivirus particle	NM_001524	3060	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV000203	Mouse Hcrt/PPOX Adeno-associate virus(AAV) plasmid	NM_010410.2	15171	Mouse	Adeno-associate virus(AAV) plasmid	GFP	3xflag (C-Terminal)	CMV	Detail
pGMLPm001154	Mouse Hcrt/PPOX Lentivirus plasmid	NM_010410	15171	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV000203	Mouse Hcrt/PPOX Adeno-associate virus(AAV) particle	NM_010410.2	15171	Mouse	Adeno-associate virus(AAV) particle	GFP	3xflag (C-Terminal)	CMV	Detail
vGMLPm001154	Mouse Hcrt/PPOX Lentivirus particle	NM_010410	15171	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

HCRT siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo3060	Pre-made Human HCRT/OX/PPOX siRNA oligo Duplex	3060	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo25723	Pre-made Rat Hcrt/orexin-A siRNA oligo Duplex	25723	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo15171	Pre-made Mouse Hcrt/PPOX siRNA oligo Duplex	15171	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo709564	Pre-made Cynomolgus/Rhesus macaque HCRT siRNA oligo Duplex	709564	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo111557774	Pre-made Cat/Feline HCRT siRNA oligo Duplex	111557774	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo607641	Pre-made Dog/Canine HCRT siRNA oligo Duplex	607641	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo281222	Pre-made Bovines/Cattle HCRT siRNA oligo Duplex	281222	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100066236	Pre-made Equine/Horse HCRT siRNA oligo Duplex	100066236	Equine/Horse	In-vitro grade; in-vivo grade	Detail

HCRT antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T60744-Ab	Human	Anti-Human HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-rg-T60744-Ab	Rat	Anti-Rat HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-mg-T60744-Ab	Mouse	Anti-Mouse HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-cynog-T60744-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-felg-T60744-Ab	Cat/Feline	Anti-Cat/Feline HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-cang-T60744-Ab	Dog/Canine	Anti-Dog/Canine HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-bovg-T60744-Ab	Bovines/Cattle	Anti-Bovines/Cattle HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-equg-T60744-Ab	Equine/Horse	Anti-Equine/Horse HCRT monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail

HCRT recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T60744-Ag	Human	Human HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T60744-Ag	Rat	Rat HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T60744-Ag	Mouse	Mouse HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T60744-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T60744-Ag	Cat/Feline	Cat/Feline HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T60744-Ag	Dog/Canine	Dog/Canine HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T60744-Ag	Bovines/Cattle	Bovines/Cattle HCRT recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T60744-Ag	Equine/Horse	Equine/Horse HCRT recombinant protein	Mammalian cell	Detail