Explore CD62L/L-selectin/SELL gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
| Target ID |
GM-T60526
|
| Target Name |
CD62L/L-selectin/SELL
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6402
|
| Gene ID |
100037404 (Felis catus), 100058663 (Equus caballus), 20343 (Mus musculus), 281485 (Bos taurus) 29259 (Rattus norvegicus), 480080 (Canis lupus familiaris), 6402 (Homo sapiens), 701419 (Macaca mulatta)
|
| Target Alternative Names |
A.11,CD62 antigen-like family member L,CD62L,L-selectin,LAM-1,LAM1,LECAM-1,LECAM1,LEU8,LNHR,LSEL,LYAM1,Leukocyte adhesion molecule 1 (LAM-1),Leukocyte surface antigen Leu-8,Leukocyte-endothelial cell adhesion molecule 1 (LECAM1),Lnhr,Ly-22,Ly-m22,Lyam-1,Lyam1,Lymph node homing receptor,PLNHR,SELL,Sell,TQ1,gp90-MEL
|
| Uniprot Accession |
P18337,P98131,P30836,P14151,Q95198
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer, Breast Cancer, Hodgkin's disease
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000020122, ENSMUSG00000026581, ENSBTAG00000011515, ENSCAFG00845002153, ENSG00000188404, ENSMMUG00000016579
|
Pre-made viral vector of CD62L/L-selectin/SELL cDNA Clones/ORF Plasmid
CD62L/L-selectin/SELL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6402 | Pre-made Human SELL/TQ1/LAM1 siRNA oligo Duplex | 6402 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29259 | Pre-made Rat Sell/A.11/LECAM-1 siRNA oligo Duplex | 29259 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20343 | Pre-made Mouse Sell/Lnhr/CD62L siRNA oligo Duplex | 20343 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701419 | Pre-made Cynomolgus/Rhesus macaque SELL siRNA oligo Duplex | 701419 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100037404 | Pre-made Cat/Feline SELL siRNA oligo Duplex | 100037404 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480080 | Pre-made Dog/Canine SELL siRNA oligo Duplex | 480080 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281485 | Pre-made Bovines/Cattle SELL siRNA oligo Duplex | 281485 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058663 | Pre-made Equine/Horse SELL siRNA oligo Duplex | 100058663 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD62L/L-selectin/SELL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60526-Ab | Human | Anti-Human CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T60526-Ab | Rat | Anti-Rat CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T60526-Ab | Mouse | Anti-Mouse CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T60526-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T60526-Ab | Cat/Feline | Anti-Cat/Feline CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T60526-Ab | Dog/Canine | Anti-Dog/Canine CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T60526-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T60526-Ab | Equine/Horse | Anti-Equine/Horse CD62L/L-selectin/SELL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD62L/L-selectin/SELL VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60526-Ag | Human | Human CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T60526-Ag | Rat | Rat CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T60526-Ag | Mouse | Mouse CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T60526-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T60526-Ag | Cat/Feline | Cat/Feline CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T60526-Ag | Dog/Canine | Dog/Canine CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T60526-Ag | Bovines/Cattle | Bovines/Cattle CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T60526-Ag | Equine/Horse | Equine/Horse CD62L/L-selectin/SELL VLP (virus-like particle) | HEK293 | Products Developing |