Explore GP6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| Target ID |
GM-T60514
|
| Target Name |
GP6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
51206
|
| Gene ID |
100055234 (Equus caballus), 100336616 (Bos taurus), 100424512 (Macaca mulatta), 101093562 (Felis catus)
243816 (Mus musculus), 484303 (Canis lupus familiaris), 51206 (Homo sapiens), 684555 (Rattus norvegicus)
|
| Target Alternative Names |
9830166G18Rik,BDPLT11,GP6,GPIV,GPVI,Glycoprotein 6,Gm469,Gp6,Gpvi,Platelet glycoprotein VI
|
| Uniprot Accession |
P0C191,Q9HCN6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease from KEGG |
ECM-receptor interaction, Platelet activation
|
| Gene Ensembl |
ENSECAG00000022569, ENSBTAG00000047175, ENSMUSG00000078810, ENSCAFG00845001852, ENSG00000088053
|
GP6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51206 | Pre-made Human GP6/GPIV/GPVI siRNA oligo Duplex | 51206 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo684555 | Pre-made Rat Gp6 siRNA oligo Duplex | 684555 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo243816 | Pre-made Mouse Gp6/Gpvi/Gm469 siRNA oligo Duplex | 243816 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100424512 | Pre-made Cynomolgus/Rhesus macaque GP6 siRNA oligo Duplex | 100424512 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093562 | Pre-made Cat/Feline GP6 siRNA oligo Duplex | 101093562 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484303 | Pre-made Dog/Canine GP6 siRNA oligo Duplex | 484303 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336616 | Pre-made Bovines/Cattle GP6 siRNA oligo Duplex | 100336616 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055234 | Pre-made Equine/Horse GP6 siRNA oligo Duplex | 100055234 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GP6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60514-Ab | Human | Anti-Human GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T60514-Ab | Rat | Anti-Rat GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T60514-Ab | Mouse | Anti-Mouse GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T60514-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T60514-Ab | Cat/Feline | Anti-Cat/Feline GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T60514-Ab | Dog/Canine | Anti-Dog/Canine GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T60514-Ab | Bovines/Cattle | Anti-Bovines/Cattle GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T60514-Ab | Equine/Horse | Anti-Equine/Horse GP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GP6 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60514-Ag | Human | Human GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T60514-Ag | Rat | Rat GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T60514-Ag | Mouse | Mouse GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T60514-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T60514-Ag | Cat/Feline | Cat/Feline GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T60514-Ag | Dog/Canine | Dog/Canine GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T60514-Ag | Bovines/Cattle | Bovines/Cattle GP6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T60514-Ag | Equine/Horse | Equine/Horse GP6 VLP (virus-like particle) | HEK293 | Products Developing |
