Explore KCNH1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T60254
|
| Target Name |
KCNH1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3756
|
| Gene ID |
100051219 (Equus caballus), 101093161 (Felis catus), 16510 (Mus musculus), 281881 (Bos taurus)
3756 (Homo sapiens), 490277 (Canis lupus familiaris), 65198 (Rattus norvegicus), 712190 (Macaca mulatta)
|
| Target Alternative Names |
EAG,EAG1,Ether-a-go-go potassium channel 1 (EAG channel 1,K(V)10.1,KCNH1,Kcnh1,Kv10.1,M-eag,Potassium voltage-gated channel subfamily H member 1,TMBTS,Voltage-gated delayed rectifier potassium channel KCNH1,Voltage-gated potassium channel subunit Kv10.1,ZLS1,bEAG,bEAG1,h-eag,hEAG,hEAG1,hEAG1),mEAG1
|
| Uniprot Accession |
Q60603,O18965,O95259,Q63472
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000000431, ENSMUSG00000058248, ENSBTAG00000008710, ENSG00000143473, ENSCAFG00845003207, ENSMMUG00000016102
|
KCNH1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3756 | Pre-made Human KCNH1/EAG/EAG1 siRNA oligo Duplex | 3756 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65198 | Pre-made Rat Kcnh1 siRNA oligo Duplex | 65198 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16510 | Pre-made Mouse Kcnh1/EAG1/M-eag siRNA oligo Duplex | 16510 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712190 | Pre-made Cynomolgus/Rhesus macaque KCNH1 siRNA oligo Duplex | 712190 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093161 | Pre-made Cat/Feline KCNH1 siRNA oligo Duplex | 101093161 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490277 | Pre-made Dog/Canine KCNH1 siRNA oligo Duplex | 490277 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281881 | Pre-made Bovines/Cattle KCNH1/EAG/bEAG siRNA oligo Duplex | 281881 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051219 | Pre-made Equine/Horse KCNH1 siRNA oligo Duplex | 100051219 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNH1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60254-Ab | Human | Anti-Human KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T60254-Ab | Rat | Anti-Rat KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T60254-Ab | Mouse | Anti-Mouse KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T60254-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T60254-Ab | Cat/Feline | Anti-Cat/Feline KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T60254-Ab | Dog/Canine | Anti-Dog/Canine KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T60254-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T60254-Ab | Equine/Horse | Anti-Equine/Horse KCNH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNH1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60254-Ag | Human | Human KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T60254-Ag | Rat | Rat KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T60254-Ag | Mouse | Mouse KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T60254-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T60254-Ag | Cat/Feline | Cat/Feline KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T60254-Ag | Dog/Canine | Dog/Canine KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T60254-Ag | Bovines/Cattle | Bovines/Cattle KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T60254-Ag | Equine/Horse | Equine/Horse KCNH1 VLP (virus-like particle) | HEK293 | Products Developing |
