Explore BMPR2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020]
| Target ID |
GM-T60213
|
| Target Name |
BMPR2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
659
|
| Gene ID |
100067195 (Equus caballus), 101096338 (Felis catus), 12168 (Mus musculus), 140590 (Rattus norvegicus)
407127 (Bos taurus), 478875 (Canis lupus familiaris), 659 (Homo sapiens), 704088 (Macaca mulatta)
|
| Target Alternative Names |
2610024H22Rik,BMP type-2 receptor,BMP-2,BMPR-2,BMPR-II,BMPR-II),BMPR2,BMPR3,BMPRII,BMR2,BRK-3,Bmpr-II,Bmpr2,Bone morphogenetic protein receptor type II (BMP type II receptor,Bone morphogenetic protein receptor type-2,Gm20272,POVD1,PPH1,T-ALK,bmprii
|
| Uniprot Accession |
O35607,Q13873
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Axon guidance, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000025141, ENSMUSG00000067336, ENSBTAG00000006420, ENSCAFG00845015459, ENSG00000204217, ENSMMUG00000009009
|
| Target Classification |
Cytokine Receptor, Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of BMPR2 cDNA Clones/ORF Plasmid
BMPR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo659 | Pre-made Human BMPR2/BMR2/PPH1 siRNA oligo Duplex | 659 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo140590 | Pre-made Rat Bmpr2/Bmpr-II siRNA oligo Duplex | 140590 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12168 | Pre-made Mouse Bmpr2/BMP-2/BRK-3 siRNA oligo Duplex | 12168 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704088 | Pre-made Cynomolgus/Rhesus macaque BMPR2 siRNA oligo Duplex | 704088 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096338 | Pre-made Cat/Feline BMPR2 siRNA oligo Duplex | 101096338 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478875 | Pre-made Dog/Canine BMPR2 siRNA oligo Duplex | 478875 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407127 | Pre-made Bovines/Cattle BMPR2/bmprii siRNA oligo Duplex | 407127 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067195 | Pre-made Equine/Horse BMPR2 siRNA oligo Duplex | 100067195 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMPR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60213-Ab | Human | Anti-Human BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T60213-Ab | Rat | Anti-Rat BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T60213-Ab | Mouse | Anti-Mouse BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T60213-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T60213-Ab | Cat/Feline | Anti-Cat/Feline BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T60213-Ab | Dog/Canine | Anti-Dog/Canine BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T60213-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T60213-Ab | Equine/Horse | Anti-Equine/Horse BMPR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
BMPR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60213-Ag | Human | Human BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T60213-Ag | Rat | Rat BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T60213-Ag | Mouse | Mouse BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T60213-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T60213-Ag | Cat/Feline | Cat/Feline BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T60213-Ag | Dog/Canine | Dog/Canine BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T60213-Ag | Bovines/Cattle | Bovines/Cattle BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T60213-Ag | Equine/Horse | Equine/Horse BMPR2 VLP (virus-like particle) | HEK293 | Products Developing |
