Explore RXRB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
| Target ID |
GM-T60077
|
| Target Name |
RXRB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6257
|
| Gene ID |
100061303 (Equus caballus), 101085801 (Felis catus), 20182 (Mus musculus), 361801 (Rattus norvegicus)
481735 (Canis lupus familiaris), 504943 (Bos taurus), 6257 (Homo sapiens), 717368 (Macaca mulatta)
|
| Target Alternative Names |
DAUDI6,H-2RIIBP,NR2B2,Nr2b2,Nuclear receptor subfamily 2 group B member 2,RCoR-1,RXR-beta,RXRB,RXRbeta,Retinoic acid receptor RXR-beta,Retinoid X receptor beta,Rub,Rxrb
|
| Uniprot Accession |
P28704,P49743,Q5TJF7,P28702
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Chemical carcinogenesis - receptor activation, Thyroid cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000023041, ENSMUSG00000039656, ENSCAFG00845020447, ENSBTAG00000000602, ENSG00000204231, ENSMMUG00000003858
|
Pre-made viral vector of RXRB cDNA Clones/ORF Plasmid
RXRB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6257 | Pre-made Human RXRB/NR2B2/DAUDI6 siRNA oligo Duplex | 6257 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361801 | Pre-made Rat Rxrb/RXR-beta siRNA oligo Duplex | 361801 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20182 | Pre-made Mouse Rxrb/Rub/Nr2b2 siRNA oligo Duplex | 20182 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717368 | Pre-made Cynomolgus/Rhesus macaque RXRB siRNA oligo Duplex | 717368 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085801 | Pre-made Cat/Feline RXRB siRNA oligo Duplex | 101085801 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481735 | Pre-made Dog/Canine RXRB/NR2B2 siRNA oligo Duplex | 481735 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504943 | Pre-made Bovines/Cattle RXRB siRNA oligo Duplex | 504943 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061303 | Pre-made Equine/Horse RXRB siRNA oligo Duplex | 100061303 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RXRB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60077-Ab | Human | Anti-Human RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T60077-Ab | Rat | Anti-Rat RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T60077-Ab | Mouse | Anti-Mouse RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T60077-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T60077-Ab | Cat/Feline | Anti-Cat/Feline RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T60077-Ab | Dog/Canine | Anti-Dog/Canine RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T60077-Ab | Bovines/Cattle | Anti-Bovines/Cattle RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T60077-Ab | Equine/Horse | Anti-Equine/Horse RXRB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RXRB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60077-Ag | Human | Human RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T60077-Ag | Rat | Rat RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T60077-Ag | Mouse | Mouse RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T60077-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T60077-Ag | Cat/Feline | Cat/Feline RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T60077-Ag | Dog/Canine | Dog/Canine RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T60077-Ag | Bovines/Cattle | Bovines/Cattle RXRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T60077-Ag | Equine/Horse | Equine/Horse RXRB recombinant protein | Mammalian cell | Detail |
