PKN1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PKN1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Target ID GM-T60003
Target Name PKN1
Gene Group ldentifer
（Target Gene ID in Homo species) 		5585
Gene ID 100856398 (Canis lupus familiaris), 101097547 (Felis catus), 102148973 (Equus caballus), 29355 (Rattus norvegicus)
320795 (Mus musculus), 509080 (Bos taurus), 5585 (Homo sapiens), 718834 (Macaca mulatta)
Target Alternative Names DBK,F730027O18Rik,PAK-1,PAK1,PKN,PKN-ALPHA,PKN1,PRK1,PRKCL1,Pkn,Pkn1,Prkcl1,Protease-activated kinase 1 (PAK-1),Protein kinase C-like 1,Protein kinase C-like PKN,Protein kinase PKN-alpha,Protein-kinase C-related kinase 1,Serine-threonine protein kinase N,Serine/threonine-protein kinase N1,Stk3
Uniprot Accession Q63433,P70268,A1A4I4,Q16512
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG PI3K-Akt signaling pathway, NOD-like receptor signaling pathway, Yersinia infection
Gene Ensembl ENSCAFG00845022295, ENSECAG00000038257, ENSMUSG00000057672, ENSBTAG00000017037, ENSG00000123143, ENSMMUG00000005727
Target Classification Kinase


Pre-made viral vector of PKN1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMAP-SPh-304Human PAK1/DBK/PAK-1 Adenovirus plasmidNM_0027415585HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAP-SPh-304Human PAK1/DBK/PAK-1 Adenovirus particleNM_0027415585HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMLP-SPm-058Mouse Pkn1/DBK/F730027O18Rik Lentivirus plasmidNM_177262320795MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPm-185Mouse Pkn1/DBK/F730027O18Rik Adenovirus plasmidNM_177262320795MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP-SPm-058Mouse Pkn1/DBK/F730027O18Rik Lentivirus particleNM_177262320795MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPm-185Mouse Pkn1/DBK/F730027O18Rik Adenovirus particleNM_177262320795MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail


PKN1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5585Pre-made Human PKN1/DBK/PKN siRNA oligo Duplex5585HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo29355Pre-made Rat Pkn1/PAK-1/Prkcl1 siRNA oligo Duplex29355RatIn-vitro grade; in-vivo gradeDetail
pGMoligo320795Pre-made Mouse Pkn1/DBK/Pkn siRNA oligo Duplex320795MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo718834Pre-made Cynomolgus/Rhesus macaque PKN1 siRNA oligo Duplex718834Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101097547Pre-made Cat/Feline PKN1 siRNA oligo Duplex101097547Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100856398Pre-made Dog/Canine PKN1 siRNA oligo Duplex100856398Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo509080Pre-made Bovines/Cattle PKN1 siRNA oligo Duplex509080Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo102148973Pre-made Equine/Horse PKN1 siRNA oligo Duplex102148973Equine/HorseIn-vitro grade; in-vivo gradeDetail


PKN1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T60003-AbHumanAnti-Human PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T60003-AbRatAnti-Rat PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T60003-AbMouseAnti-Mouse PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T60003-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T60003-AbCat/FelineAnti-Cat/Feline PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T60003-AbDog/CanineAnti-Dog/Canine PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T60003-AbBovines/CattleAnti-Bovines/Cattle PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T60003-AbEquine/HorseAnti-Equine/Horse PKN1 monoclonal antibodymabTherapeutics Target antibodyDetail


PKN1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T60003-AgHumanHuman PKN1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T60003-AgRatRat PKN1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T60003-AgMouseMouse PKN1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T60003-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PKN1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T60003-AgCat/FelineCat/Feline PKN1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T60003-AgDog/CanineDog/Canine PKN1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T60003-AgBovines/CattleBovines/Cattle PKN1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T60003-AgEquine/HorseEquine/Horse PKN1 recombinant proteinMammalian cellDetail