Explore PD-ECGF/TYMP gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
| Target ID |
GM-T59929
|
| Target Name |
PD-ECGF/TYMP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1890
|
| Gene ID |
100146854 (Equus caballus), 1890 (Homo sapiens), 72962 (Mus musculus)
|
| Target Alternative Names |
2900072D10Rik,ECGF,ECGF1,Ecgf1,Gliostatin,MEDPS1,MNGIE,MTDPS1,PD-ECGF,PDECGF,Pdgfec,Platelet-derived endothelial cell growth factor (PD-ECGF),TP,TYMP,TdRPase,Thymidine phosphorylase,Tymp,hPD-ECGF
|
| Uniprot Accession |
P19971,Q99N42
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Bladder cancer
|
| Gene Ensembl |
ENSECAG00000001072, ENSG00000025708, ENSMUSG00000022615
|
Pre-made viral vector of PD-ECGF/TYMP cDNA Clones/ORF Plasmid
PD-ECGF/TYMP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1890 | Pre-made Human TYMP/TP/ECGF siRNA oligo Duplex | 1890 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72962 | Pre-made Mouse Tymp/TP/Ecgf1 siRNA oligo Duplex | 72962 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146854 | Pre-made Equine/Horse TYMP siRNA oligo Duplex | 100146854 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PD-ECGF/TYMP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T59929-Ab | Human | Anti-Human PD-ECGF/TYMP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T59929-Ab | Mouse | Anti-Mouse PD-ECGF/TYMP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T59929-Ab | Equine/Horse | Anti-Equine/Horse PD-ECGF/TYMP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PD-ECGF/TYMP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T59929-Ag | Human | Human PD-ECGF/TYMP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T59929-Ag | Mouse | Mouse PD-ECGF/TYMP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T59929-Ag | Equine/Horse | Equine/Horse PD-ECGF/TYMP recombinant protein | Mammalian cell | Detail |