Explore AVPR1B/V1BR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T59881
|
| Target Name |
AVPR1B/V1BR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
553
|
| Gene ID |
100055260 (Equus caballus), 100909648 (Rattus norvegicus), 101088713 (Felis catus), 26361 (Mus musculus)
282861 (Bos taurus), 488578 (Canis lupus familiaris), 553 (Homo sapiens), 695963 (Macaca mulatta)
|
| Target Alternative Names |
AVPR V1b,AVPR V3,AVPR1B,AVPR3,Antidiuretic hormone receptor 1b,Avpr1b,V1BR,V1bR,V3/V1b,VIBR,VPR3,Vasopressin V1b receptor,Vasopressin V3 receptor
|
| Uniprot Accession |
P48974,Q9WU02,P47901
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
|
| Gene Ensembl |
ENSECAG00000013720, ENSMUSG00000026432, ENSBTAG00000017301, ENSCAFG00845028059, ENSG00000198049
|
| Target Classification |
GPCR
|
Pre-made viral vector of AVPR1B/V1BR cDNA Clones/ORF Plasmid
AVPR1B/V1BR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo553 | Pre-made Human AVPR1B/V1bR/VPR3 siRNA oligo Duplex | 553 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100909648 | Pre-made Rat Avpr1b/V1bR/AVPR V3 siRNA oligo Duplex | 100909648 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26361 | Pre-made Mouse Avpr1b/VIBR/VPR3 siRNA oligo Duplex | 26361 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695963 | Pre-made Cynomolgus/Rhesus macaque AVPR1B siRNA oligo Duplex | 695963 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088713 | Pre-made Cat/Feline AVPR1B siRNA oligo Duplex | 101088713 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488578 | Pre-made Dog/Canine AVPR1B siRNA oligo Duplex | 488578 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282861 | Pre-made Bovines/Cattle AVPR1B/AVPR3 siRNA oligo Duplex | 282861 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055260 | Pre-made Equine/Horse AVPR1B siRNA oligo Duplex | 100055260 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AVPR1B/V1BR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T59881-Ab | Human | Anti-Human AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T59881-Ab | Rat | Anti-Rat AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T59881-Ab | Mouse | Anti-Mouse AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T59881-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T59881-Ab | Cat/Feline | Anti-Cat/Feline AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T59881-Ab | Dog/Canine | Anti-Dog/Canine AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T59881-Ab | Bovines/Cattle | Anti-Bovines/Cattle AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T59881-Ab | Equine/Horse | Anti-Equine/Horse AVPR1B/V1BR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
AVPR1B/V1BR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T59881-Ag | Human | Human AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T59881-Ag | Rat | Rat AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T59881-Ag | Mouse | Mouse AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T59881-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T59881-Ag | Cat/Feline | Cat/Feline AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T59881-Ag | Dog/Canine | Dog/Canine AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T59881-Ag | Bovines/Cattle | Bovines/Cattle AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T59881-Ag | Equine/Horse | Equine/Horse AVPR1B/V1BR VLP (virus-like particle) | HEK293 | Products Developing |
