Explore HTR4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
| Target ID |
GM-T59679
|
| Target Name |
HTR4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3360
|
| Gene ID |
100034053 (Equus caballus), 101088723 (Felis catus), 15562 (Mus musculus), 25324 (Rattus norvegicus)
317708 (Bos taurus), 3360 (Homo sapiens), 489198 (Canis lupus familiaris), 710046 (Macaca mulatta)
|
| Target Alternative Names |
5-HT-4,5-HT4,5-HT4R,5-HT<4L>,5-hydroxytryptamine receptor 4,5HTR4,HTR4,Htr4,Serotonin receptor 4
|
| Uniprot Accession |
P97288,Q62758,Q13639
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse
|
| Gene Ensembl |
ENSECAG00000013365, ENSMUSG00000026322, ENSBTAG00000010837, ENSG00000164270, ENSCAFG00845010692, ENSMMUG00000016913
|
| Target Classification |
GPCR
|
Pre-made viral vector of HTR4 cDNA Clones/ORF Plasmid
HTR4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3360 | Pre-made Human HTR4/5-HT4/5-HT4R siRNA oligo Duplex | 3360 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25324 | Pre-made Rat Htr4 siRNA oligo Duplex | 25324 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15562 | Pre-made Mouse Htr4/5-HT4/5HTR4 siRNA oligo Duplex | 15562 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710046 | Pre-made Cynomolgus/Rhesus macaque HTR4 siRNA oligo Duplex | 710046 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088723 | Pre-made Cat/Feline HTR4 siRNA oligo Duplex | 101088723 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489198 | Pre-made Dog/Canine HTR4 siRNA oligo Duplex | 489198 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317708 | Pre-made Bovines/Cattle HTR4 siRNA oligo Duplex | 317708 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034053 | Pre-made Equine/Horse HTR4 siRNA oligo Duplex | 100034053 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTR4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T59679-Ab | Human | Anti-Human HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T59679-Ab | Rat | Anti-Rat HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T59679-Ab | Mouse | Anti-Mouse HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T59679-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T59679-Ab | Cat/Feline | Anti-Cat/Feline HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T59679-Ab | Dog/Canine | Anti-Dog/Canine HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T59679-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T59679-Ab | Equine/Horse | Anti-Equine/Horse HTR4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HTR4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T59679-Ag | Human | Human HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T59679-Ag | Rat | Rat HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T59679-Ag | Mouse | Mouse HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T59679-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T59679-Ag | Cat/Feline | Cat/Feline HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T59679-Ag | Dog/Canine | Dog/Canine HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T59679-Ag | Bovines/Cattle | Bovines/Cattle HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T59679-Ag | Equine/Horse | Equine/Horse HTR4 VLP (virus-like particle) | HEK293 | Products Developing |
