Explore GHSR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010]
| Target ID |
GM-T59604
|
| Target Name |
GHSR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2693
|
| Gene ID |
100057865 (Equus caballus), 100101479 (Canis lupus familiaris), 101083540 (Felis catus), 208188 (Mus musculus)
2693 (Homo sapiens), 514203 (Bos taurus), 694587 (Macaca mulatta), 84022 (Rattus norvegicus)
|
| Target Alternative Names |
C530020I22Rik,GH-releasing peptide receptor (GHRP),GHDP,GHRP,GHS-R,GHS-R1a,GHSR,GHSR-1a,Ghrelin receptor,Ghsr,Ghsr1a,Growth hormone secretagogue receptor type 1
|
| Uniprot Accession |
Q99P50,Q92847,O08725
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000017722, ENSCAFG00845025708, ENSMUSG00000051136, ENSG00000121853, ENSBTAG00000010874, ENSMMUG00000004194
|
| Target Classification |
GPCR
|
Pre-made viral vector of GHSR cDNA Clones/ORF Plasmid
GHSR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2693 | Pre-made Human GHSR/GHDP/GHS-R1a siRNA oligo Duplex | 2693 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84022 | Pre-made Rat Ghsr siRNA oligo Duplex | 84022 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo208188 | Pre-made Mouse Ghsr/GHRP/GHS-R siRNA oligo Duplex | 208188 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694587 | Pre-made Cynomolgus/Rhesus macaque GHSR siRNA oligo Duplex | 694587 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083540 | Pre-made Cat/Feline GHSR siRNA oligo Duplex | 101083540 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100101479 | Pre-made Dog/Canine GHSR siRNA oligo Duplex | 100101479 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514203 | Pre-made Bovines/Cattle GHSR siRNA oligo Duplex | 514203 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057865 | Pre-made Equine/Horse GHSR siRNA oligo Duplex | 100057865 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GHSR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T59604-Ab | Human | Anti-Human GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T59604-Ab | Rat | Anti-Rat GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T59604-Ab | Mouse | Anti-Mouse GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T59604-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T59604-Ab | Cat/Feline | Anti-Cat/Feline GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T59604-Ab | Dog/Canine | Anti-Dog/Canine GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T59604-Ab | Bovines/Cattle | Anti-Bovines/Cattle GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T59604-Ab | Equine/Horse | Anti-Equine/Horse GHSR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GHSR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T59604-Ag | Human | Human GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T59604-Ag | Rat | Rat GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T59604-Ag | Mouse | Mouse GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T59604-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T59604-Ag | Cat/Feline | Cat/Feline GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T59604-Ag | Dog/Canine | Dog/Canine GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T59604-Ag | Bovines/Cattle | Bovines/Cattle GHSR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T59604-Ag | Equine/Horse | Equine/Horse GHSR VLP (virus-like particle) | HEK293 | Products Developing |
