Explore IGF2R/CD222 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
| Target ID |
GM-T59550
|
| Target Name |
IGF2R/CD222
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3482
|
| Gene ID |
100058539 (Equus caballus), 100500935 (Felis catus), 16004 (Mus musculus), 25151 (Rattus norvegicus)
281849 (Bos taurus), 3482 (Homo sapiens), 484067 (Canis lupus familiaris), 703220 (Macaca mulatta)
|
| Target Alternative Names |
IGF2R,Igf2r,CD222,CI-MPR,Mpr300,M6P/IGF2R,Igfr2,IGF-IIR,CIMPR,MPR1,MPRI,M6P-R,MPR300,CI-M6PR,MPR 300
|
| Uniprot Accession |
Q07113,P08169,P11717
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Lysosome
|
| Gene Ensembl |
ENSECAG00000019509, ENSMUSG00000023830, ENSBTAG00000002402, ENSG00000197081, ENSCAFG00845002089, ENSMMUG00000015658
|
| Target Classification |
Tumor-associated antigen (TAA)
|
IGF2R/CD222 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3482 | Pre-made Human IGF2R/MPR1/MPRI siRNA oligo Duplex | 3482 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25151 | Pre-made Rat Igf2r/Igfr2/IGF-IIR siRNA oligo Duplex | 25151 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16004 | Pre-made Mouse Igf2r/CD222/CI-MPR siRNA oligo Duplex | 16004 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703220 | Pre-made Cynomolgus/Rhesus macaque IGF2R siRNA oligo Duplex | 703220 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100500935 | Pre-made Cat/Feline IGF2R siRNA oligo Duplex | 100500935 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484067 | Pre-made Dog/Canine IGF2R siRNA oligo Duplex | 484067 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281849 | Pre-made Bovines/Cattle IGF2R/CIMPR/CI-MPR siRNA oligo Duplex | 281849 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058539 | Pre-made Equine/Horse IGF2R siRNA oligo Duplex | 100058539 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IGF2R/CD222 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T59550-Ab | Human | Anti-Human IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T59550-Ab | Rat | Anti-Rat IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T59550-Ab | Mouse | Anti-Mouse IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T59550-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T59550-Ab | Cat/Feline | Anti-Cat/Feline IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T59550-Ab | Dog/Canine | Anti-Dog/Canine IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T59550-Ab | Bovines/Cattle | Anti-Bovines/Cattle IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T59550-Ab | Equine/Horse | Anti-Equine/Horse IGF2R/CD222 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IGF2R/CD222 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T59550-Ag | Human | Human IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T59550-Ag | Rat | Rat IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T59550-Ag | Mouse | Mouse IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T59550-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T59550-Ag | Cat/Feline | Cat/Feline IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T59550-Ag | Dog/Canine | Dog/Canine IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T59550-Ag | Bovines/Cattle | Bovines/Cattle IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T59550-Ag | Equine/Horse | Equine/Horse IGF2R/CD222 VLP (virus-like particle) | HEK293 | Products Developing |
