PDGFR beta/CD140b/PDGFRB Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PDGFR beta/CD140b/PDGFRB gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

Pre-made viral vector of PDGFR beta/CD140b/PDGFRB cDNA Clones/ORF Plasmid

PDGFR beta/CD140b/PDGFRB siRNA/miRNA/oligo for RNA interfence (RNAi)

PDGFR beta/CD140b/PDGFRB antibody/GMab

PDGFR beta/CD140b/PDGFRB VLP (virus-like particle)/protein