Explore HTR3B gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
| Target ID |
GM-T58940
|
| Target Name |
HTR3B
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9177
|
| Gene ID |
100070774 (Equus caballus), 102899836 (Felis catus), 541055 (Bos taurus), 57014 (Mus musculus) 58963 (Rattus norvegicus), 611236 (Canis lupus familiaris), 694830 (Macaca mulatta), 9177 (Homo sapiens)
|
| Target Alternative Names |
5-HT3-B,5-HT3B,5-hydroxytryptamine receptor 3B,HTR3B,Htr3b,Serotonin receptor 3B
|
| Uniprot Accession |
Q9JHJ5,Q9JJ16,O95264
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Serotonergic synapse, Taste transduction
|
| Gene Ensembl |
ENSBTAG00000031330, ENSMUSG00000008590, ENSCAFG00845000289, ENSMMUG00000007079, ENSG00000149305
|
HTR3B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9177 | Pre-made Human HTR3B/5-HT3B siRNA oligo Duplex | 9177 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58963 | Pre-made Rat Htr3b siRNA oligo Duplex | 58963 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo57014 | Pre-made Mouse Htr3b/5-HT3B siRNA oligo Duplex | 57014 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694830 | Pre-made Cynomolgus/Rhesus macaque HTR3B siRNA oligo Duplex | 694830 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102899836 | Pre-made Cat/Feline HTR3B siRNA oligo Duplex | 102899836 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611236 | Pre-made Dog/Canine HTR3B siRNA oligo Duplex | 611236 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541055 | Pre-made Bovines/Cattle HTR3B siRNA oligo Duplex | 541055 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070774 | Pre-made Equine/Horse HTR3B siRNA oligo Duplex | 100070774 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTR3B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T58940-Ab | Human | Anti-Human HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T58940-Ab | Rat | Anti-Rat HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T58940-Ab | Mouse | Anti-Mouse HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T58940-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T58940-Ab | Cat/Feline | Anti-Cat/Feline HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T58940-Ab | Dog/Canine | Anti-Dog/Canine HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T58940-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T58940-Ab | Equine/Horse | Anti-Equine/Horse HTR3B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HTR3B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T58940-Ag | Human | Human HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T58940-Ag | Rat | Rat HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T58940-Ag | Mouse | Mouse HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T58940-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T58940-Ag | Cat/Feline | Cat/Feline HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T58940-Ag | Dog/Canine | Dog/Canine HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T58940-Ag | Bovines/Cattle | Bovines/Cattle HTR3B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T58940-Ag | Equine/Horse | Equine/Horse HTR3B VLP (virus-like particle) | HEK293 | Products Developing |