Explore GlyT2/SLC6A5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T58937
|
| Target Name |
GlyT2/SLC6A5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9152
|
| Gene ID |
100057380 (Equus caballus), 101085314 (Felis catus), 104245 (Mus musculus), 171148 (Rattus norvegicus)
528050 (Bos taurus), 612095 (Canis lupus familiaris), 704703 (Macaca mulatta), 9152 (Homo sapiens)
|
| Target Alternative Names |
GLYT-2,GLYT2,GlyT-2,GlyT2,Glyt2,HKPX3,NET1,SLC6A5,Slc6a5,Sodium- and chloride-dependent glycine transporter 2,Solute carrier family 6 member 5,prestin
|
| Uniprot Accession |
Q761V0,P58295,Q9Y345
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000022340, ENSMUSG00000039728, ENSBTAG00000014300, ENSCAFG00845021856, ENSG00000165970
|
GlyT2/SLC6A5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9152 | Pre-made Human SLC6A5/NET1/GLYT2 siRNA oligo Duplex | 9152 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171148 | Pre-made Rat Slc6a5/GLYT2 siRNA oligo Duplex | 171148 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo104245 | Pre-made Mouse Slc6a5/Glyt2/prestin siRNA oligo Duplex | 104245 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704703 | Pre-made Cynomolgus/Rhesus macaque SLC6A5 siRNA oligo Duplex | 704703 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085314 | Pre-made Cat/Feline SLC6A5 siRNA oligo Duplex | 101085314 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612095 | Pre-made Dog/Canine SLC6A5 siRNA oligo Duplex | 612095 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528050 | Pre-made Bovines/Cattle SLC6A5 siRNA oligo Duplex | 528050 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057380 | Pre-made Equine/Horse SLC6A5 siRNA oligo Duplex | 100057380 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GlyT2/SLC6A5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T58937-Ab | Human | Anti-Human GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T58937-Ab | Rat | Anti-Rat GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T58937-Ab | Mouse | Anti-Mouse GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T58937-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T58937-Ab | Cat/Feline | Anti-Cat/Feline GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T58937-Ab | Dog/Canine | Anti-Dog/Canine GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T58937-Ab | Bovines/Cattle | Anti-Bovines/Cattle GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T58937-Ab | Equine/Horse | Anti-Equine/Horse GlyT2/SLC6A5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GlyT2/SLC6A5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T58937-Ag | Human | Human GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T58937-Ag | Rat | Rat GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T58937-Ag | Mouse | Mouse GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T58937-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T58937-Ag | Cat/Feline | Cat/Feline GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T58937-Ag | Dog/Canine | Dog/Canine GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T58937-Ag | Bovines/Cattle | Bovines/Cattle GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T58937-Ag | Equine/Horse | Equine/Horse GlyT2/SLC6A5 VLP (virus-like particle) | HEK293 | Products Developing |
