Explore PPME1/PME-1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
| Target ID |
GM-T58307
|
| Target Name |
PPME1/PME-1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
51400
|
| Gene ID |
100065317 (Equus caballus), 101094949 (Felis catus), 361613 (Rattus norvegicus), 51400 (Homo sapiens) 535390 (Bos taurus), 612812 (Canis lupus familiaris), 718858 (Macaca mulatta), 72590 (Mus musculus)
|
| Target Alternative Names |
1110069N17Rik,2700017M01Rik,ABDH19,PME-1,PME1MGC133824,PPME1,Pme1,Ppme1,Protein phosphatase methylesterase 1,RGD1309683
|
| Uniprot Accession |
Q4FZT2,Q9Y570,Q58DN4,Q8BVQ5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000010756, ENSG00000214517, ENSBTAG00000027612, ENSCAFG00845006643, ENSMMUG00000017398, ENSMUSG00000030718
|
Pre-made viral vector of PPME1/PME-1 cDNA Clones/ORF Plasmid
PPME1/PME-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51400 | Pre-made Human PPME1/PME-1/ABDH19 siRNA oligo Duplex | 51400 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361613 | Pre-made Rat Ppme1/PME-1/RGD1309683 siRNA oligo Duplex | 361613 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72590 | Pre-made Mouse Ppme1/Pme1/PME-1 siRNA oligo Duplex | 72590 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718858 | Pre-made Cynomolgus/Rhesus macaque PPME1 siRNA oligo Duplex | 718858 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094949 | Pre-made Cat/Feline PPME1 siRNA oligo Duplex | 101094949 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612812 | Pre-made Dog/Canine PPME1 siRNA oligo Duplex | 612812 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535390 | Pre-made Bovines/Cattle PPME1/PME1MGC133824 siRNA oligo Duplex | 535390 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065317 | Pre-made Equine/Horse PPME1 siRNA oligo Duplex | 100065317 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PPME1/PME-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T58307-Ab | Human | Anti-Human PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T58307-Ab | Rat | Anti-Rat PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T58307-Ab | Mouse | Anti-Mouse PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T58307-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T58307-Ab | Cat/Feline | Anti-Cat/Feline PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T58307-Ab | Dog/Canine | Anti-Dog/Canine PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T58307-Ab | Bovines/Cattle | Anti-Bovines/Cattle PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T58307-Ab | Equine/Horse | Anti-Equine/Horse PPME1/PME-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PPME1/PME-1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T58307-Ag | Human | Human PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T58307-Ag | Rat | Rat PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T58307-Ag | Mouse | Mouse PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T58307-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T58307-Ag | Cat/Feline | Cat/Feline PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T58307-Ag | Dog/Canine | Dog/Canine PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T58307-Ag | Bovines/Cattle | Bovines/Cattle PPME1/PME-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T58307-Ag | Equine/Horse | Equine/Horse PPME1/PME-1 recombinant protein | Mammalian cell | Detail |