Explore CD80 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
| Target ID |
GM-T58238
|
| Target Name |
CD80
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
941
|
| Gene ID |
100071012 (Equus caballus), 12519 (Mus musculus), 25408 (Rattus norvegicus), 403765 (Canis lupus familiaris)
407131 (Bos taurus), 493786 (Felis catus), 732518 (Macaca mulatta), 941 (Homo sapiens)
|
| Target Alternative Names |
Activation B7-1 antigen,B7,B7-1,B7.1,B71,BB1,CD28LG,CD28LG1,CD80,CTLA-4 counter-receptor B7.1 (B7),Cd28l,Cd80,LAB7,Ly-53,Ly53,MIC17,T-lymphocyte activation antigen CD80,TSA1
|
| Uniprot Accession |
Q00609,P33681
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, Lipoid nephrosis
|
| Disease from KEGG |
Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Autoimmune thyroid disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis
|
| Gene Ensembl |
ENSECAG00000002211, ENSMUSG00000075122, ENSCAFG00845016834, ENSBTAG00000018059, ENSMMUG00000016367, ENSG00000121594
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD80 cDNA Clones/ORF Plasmid
CD80 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo941 | Pre-made Human CD80/B7/BB1 siRNA oligo Duplex | 941 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25408 | Pre-made Rat Cd80/B7-1 siRNA oligo Duplex | 25408 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12519 | Pre-made Mouse Cd80/B71/Ly53 siRNA oligo Duplex | 12519 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo732518 | Pre-made Cynomolgus/Rhesus macaque CD80/B7.1 siRNA oligo Duplex | 732518 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493786 | Pre-made Cat/Feline CD80 siRNA oligo Duplex | 493786 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403765 | Pre-made Dog/Canine CD80 siRNA oligo Duplex | 403765 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407131 | Pre-made Bovines/Cattle CD80 siRNA oligo Duplex | 407131 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071012 | Pre-made Equine/Horse CD80 siRNA oligo Duplex | 100071012 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD80 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T58238-Ab | Human | Anti-Human CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T58238-Ab | Rat | Anti-Rat CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T58238-Ab | Mouse | Anti-Mouse CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T58238-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T58238-Ab | Cat/Feline | Anti-Cat/Feline CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T58238-Ab | Dog/Canine | Anti-Dog/Canine CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T58238-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T58238-Ab | Equine/Horse | Anti-Equine/Horse CD80 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD80 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T58238-Ag | Human | Human CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T58238-Ag | Rat | Rat CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T58238-Ag | Mouse | Mouse CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T58238-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T58238-Ag | Cat/Feline | Cat/Feline CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T58238-Ag | Dog/Canine | Dog/Canine CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T58238-Ag | Bovines/Cattle | Bovines/Cattle CD80 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T58238-Ag | Equine/Horse | Equine/Horse CD80 VLP (virus-like particle) | HEK293 | Products Developing |
