Explore ABCG2/CD338 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
| Target ID |
GM-T56556
|
| Target Name |
ABCG2/CD338
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9429
|
| Gene ID |
100034164 (Equus caballus), 101094017 (Felis catus), 26357 (Mus musculus), 312382 (Rattus norvegicus) 478472 (Canis lupus familiaris), 536203 (Bos taurus), 574307 (Macaca mulatta), 9429 (Homo sapiens)
|
| Target Alternative Names |
ABC15,ABCG2,ABCG3,ABCP,ATP-binding cassette sub-family G member 2,Abcg2,BCRP,BCRP1,BMDP,Bcrp,Bcrp1,Breast cancer resistance protein,Broad substrate specificity ATP-binding cassette transporter ABCG2,CD338,CDw338,CDw388,EST157481,GOUT1,MRX,MXR,MXR-1,MXR1,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,UAQTL1,Urate exporter
|
| Uniprot Accession |
Q7TMS5,Q80W57,Q4GZT4,Q5MB13,Q9UNQ0
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Antifolate resistance, ABC transporters, Bile secretion
|
| Gene Ensembl |
ENSECAG00000009773, ENSMUSG00000029802, ENSCAFG00845016353, ENSBTAG00000017704, ENSMMUG00000008797, ENSG00000118777
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ABCG2/CD338 cDNA Clones/ORF Plasmid
ABCG2/CD338 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9429 | Pre-made Human ABCG2/MRX/MXR siRNA oligo Duplex | 9429 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312382 | Pre-made Rat Abcg2/Bcrp/BCRP1 siRNA oligo Duplex | 312382 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26357 | Pre-made Mouse Abcg2/MXR/ABCP siRNA oligo Duplex | 26357 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574307 | Pre-made Cynomolgus/Rhesus macaque ABCG2/ABCG3 siRNA oligo Duplex | 574307 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094017 | Pre-made Cat/Feline ABCG2 siRNA oligo Duplex | 101094017 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478472 | Pre-made Dog/Canine ABCG2/BCRP siRNA oligo Duplex | 478472 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536203 | Pre-made Bovines/Cattle ABCG2 siRNA oligo Duplex | 536203 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034164 | Pre-made Equine/Horse ABCG2 siRNA oligo Duplex | 100034164 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ABCG2/CD338 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T56556-Ab | Human | Anti-Human ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T56556-Ab | Rat | Anti-Rat ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T56556-Ab | Mouse | Anti-Mouse ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T56556-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T56556-Ab | Cat/Feline | Anti-Cat/Feline ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T56556-Ab | Dog/Canine | Anti-Dog/Canine ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T56556-Ab | Bovines/Cattle | Anti-Bovines/Cattle ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T56556-Ab | Equine/Horse | Anti-Equine/Horse ABCG2/CD338 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ABCG2/CD338 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T56556-Ag | Human | Human ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T56556-Ag | Rat | Rat ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T56556-Ag | Mouse | Mouse ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T56556-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T56556-Ag | Cat/Feline | Cat/Feline ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T56556-Ag | Dog/Canine | Dog/Canine ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T56556-Ag | Bovines/Cattle | Bovines/Cattle ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T56556-Ag | Equine/Horse | Equine/Horse ABCG2/CD338 VLP (virus-like particle) | HEK293 | Products Developing |