Explore TNFAIP3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
| Target ID |
GM-T56474
|
| Target Name |
TNFAIP3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7128
|
| Gene ID |
100073197 (Equus caballus), 101083682 (Felis catus), 21929 (Mus musculus), 484006 (Canis lupus familiaris) 508105 (Bos taurus), 683206 (Rattus norvegicus), 704130 (Macaca mulatta), 7128 (Homo sapiens)
|
| Target Alternative Names |
A20,AIFBL1,AISBL,OTU domain-containing protein 7C,OTUD7C,Putative DNA-binding protein A20,TNF alpha-induced protein 3,TNFA1P2,TNFAIP3,Tnfaip3,Tnfip3,Tumor necrosis factor alpha-induced protein 3,Zinc finger protein A20
|
| Uniprot Accession |
Q60769,P21580
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer, IgA glomerulonephritis
|
| Disease from KEGG |
NF-kappa B signaling pathway, NOD-like receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Measles, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000009626, ENSMUSG00000019850, ENSCAFG00845006723, ENSBTAG00000000436, ENSMMUG00000008869, ENSG00000118503
|
Pre-made viral vector of TNFAIP3 cDNA Clones/ORF Plasmid
TNFAIP3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7128 | Pre-made Human TNFAIP3/A20/AISBL siRNA oligo Duplex | 7128 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo683206 | Pre-made Rat Tnfaip3 siRNA oligo Duplex | 683206 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21929 | Pre-made Mouse Tnfaip3/A20/Tnfip3 siRNA oligo Duplex | 21929 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704130 | Pre-made Cynomolgus/Rhesus macaque TNFAIP3 siRNA oligo Duplex | 704130 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083682 | Pre-made Cat/Feline TNFAIP3 siRNA oligo Duplex | 101083682 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484006 | Pre-made Dog/Canine TNFAIP3 siRNA oligo Duplex | 484006 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508105 | Pre-made Bovines/Cattle TNFAIP3 siRNA oligo Duplex | 508105 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100073197 | Pre-made Equine/Horse TNFAIP3 siRNA oligo Duplex | 100073197 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNFAIP3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T56474-Ab | Human | Anti-Human TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T56474-Ab | Rat | Anti-Rat TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T56474-Ab | Mouse | Anti-Mouse TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T56474-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T56474-Ab | Cat/Feline | Anti-Cat/Feline TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T56474-Ab | Dog/Canine | Anti-Dog/Canine TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T56474-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T56474-Ab | Equine/Horse | Anti-Equine/Horse TNFAIP3 monoclonal antibody | mab | Therapeutics Target antibody, Cytokine antibody | Detail |
TNFAIP3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T56474-Ag | Human | Human TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T56474-Ag | Rat | Rat TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T56474-Ag | Mouse | Mouse TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T56474-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T56474-Ag | Cat/Feline | Cat/Feline TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T56474-Ag | Dog/Canine | Dog/Canine TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T56474-Ag | Bovines/Cattle | Bovines/Cattle TNFAIP3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T56474-Ag | Equine/Horse | Equine/Horse TNFAIP3 recombinant protein | Mammalian cell | Detail |