Explore LSS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]
| Target ID |
GM-T56175
|
| Target Name |
LSS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4047
|
| Gene ID |
100055292 (Equus caballus), 101080651 (Felis catus), 16987 (Mus musculus), 4047 (Homo sapiens)
491611 (Canis lupus familiaris), 615906 (Bos taurus), 709227 (Macaca mulatta), 81681 (Rattus norvegicus)
|
| Target Alternative Names |
2,2810025N20Rik,3-epoxysqualene--lanosterol cyclase,APMR4,CTRCT44,D10Ertd116e,HYPT14,LSS,Lanosterol synthase,Lss,OSC,Osc,Oxidosqualene--lanosterol cyclase (OSC,hOSC)
|
| Uniprot Accession |
Q8BLN5,P48449,P84466,P48450
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Steroid biosynthesis, Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000008899, ENSMUSG00000033105, ENSG00000160285, ENSCAFG00845024919, ENSBTAG00000018936, ENSMMUG00000022329
|
Pre-made viral vector of LSS cDNA Clones/ORF Plasmid
LSS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4047 | Pre-made Human LSS/OSC/APMR4 siRNA oligo Duplex | 4047 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81681 | Pre-made Rat Lss siRNA oligo Duplex | 81681 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16987 | Pre-made Mouse Lss/Osc/D10Ertd116e siRNA oligo Duplex | 16987 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709227 | Pre-made Cynomolgus/Rhesus macaque LSS siRNA oligo Duplex | 709227 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080651 | Pre-made Cat/Feline LSS siRNA oligo Duplex | 101080651 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491611 | Pre-made Dog/Canine LSS siRNA oligo Duplex | 491611 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615906 | Pre-made Bovines/Cattle LSS siRNA oligo Duplex | 615906 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055292 | Pre-made Equine/Horse LSS siRNA oligo Duplex | 100055292 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LSS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T56175-Ab | Human | Anti-Human LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T56175-Ab | Rat | Anti-Rat LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T56175-Ab | Mouse | Anti-Mouse LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T56175-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T56175-Ab | Cat/Feline | Anti-Cat/Feline LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T56175-Ab | Dog/Canine | Anti-Dog/Canine LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T56175-Ab | Bovines/Cattle | Anti-Bovines/Cattle LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T56175-Ab | Equine/Horse | Anti-Equine/Horse LSS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
LSS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T56175-Ag | Human | Human LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T56175-Ag | Rat | Rat LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T56175-Ag | Mouse | Mouse LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T56175-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T56175-Ag | Cat/Feline | Cat/Feline LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T56175-Ag | Dog/Canine | Dog/Canine LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T56175-Ag | Bovines/Cattle | Bovines/Cattle LSS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T56175-Ag | Equine/Horse | Equine/Horse LSS recombinant protein | Mammalian cell | Detail |
