Explore MERTK gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]
| Target ID |
GM-T55781
|
| Target Name |
MERTK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10461
|
| Gene ID |
100064727 (Equus caballus), 101084099 (Felis catus), 10461 (Homo sapiens), 17289 (Mus musculus)
483060 (Canis lupus familiaris), 504429 (Bos taurus), 65037 (Rattus norvegicus), 698330 (Macaca mulatta)
|
| Target Alternative Names |
MERTK,Mertk,MER,RP38,c-Eyk,c-mer,Tyro12,Eyk,Mer,Nyk,nmf12,rdy
|
| Uniprot Accession |
Q12866,Q60805,P57097
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000023970, ENSG00000153208, ENSMUSG00000014361, ENSCAFG00845010081, ENSBTAG00000005828, ENSMMUG00000010066
|
| Target Classification |
Kinase, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
MERTK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10461 | Pre-made Human MERTK/MER/RP38 siRNA oligo Duplex | 10461 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65037 | Pre-made Rat Mertk/rdy siRNA oligo Duplex | 65037 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17289 | Pre-made Mouse Mertk/Eyk/Mer siRNA oligo Duplex | 17289 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698330 | Pre-made Cynomolgus/Rhesus macaque MERTK siRNA oligo Duplex | 698330 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084099 | Pre-made Cat/Feline MERTK siRNA oligo Duplex | 101084099 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483060 | Pre-made Dog/Canine MERTK siRNA oligo Duplex | 483060 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504429 | Pre-made Bovines/Cattle MERTK siRNA oligo Duplex | 504429 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064727 | Pre-made Equine/Horse MERTK siRNA oligo Duplex | 100064727 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MERTK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T55781-Ab | Human | Anti-Human MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T55781-Ab | Rat | Anti-Rat MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T55781-Ab | Mouse | Anti-Mouse MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T55781-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T55781-Ab | Cat/Feline | Anti-Cat/Feline MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T55781-Ab | Dog/Canine | Anti-Dog/Canine MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T55781-Ab | Bovines/Cattle | Anti-Bovines/Cattle MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T55781-Ab | Equine/Horse | Anti-Equine/Horse MERTK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MERTK VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T55781-Ag | Human | Human MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T55781-Ag | Rat | Rat MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T55781-Ag | Mouse | Mouse MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T55781-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T55781-Ag | Cat/Feline | Cat/Feline MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T55781-Ag | Dog/Canine | Dog/Canine MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T55781-Ag | Bovines/Cattle | Bovines/Cattle MERTK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T55781-Ag | Equine/Horse | Equine/Horse MERTK VLP (virus-like particle) | HEK293 | Products Developing |
