Explore IL-28B/IFNL3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
| Target ID |
GM-T55242
|
| Target Name |
IL-28B/IFNL3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
282617
|
| Gene ID |
119870346 (Canis lupus familiaris), 282617 (Homo sapiens), 695997 (Macaca mulatta)
|
| Target Alternative Names |
Cytokine Zcyto22,IFN-lambda-3,IFN-lambda-4,IFNL3,IL-28B,IL-28C,IL28A,IL28B,IL28C,Interferon lambda-3,Interleukin-28B (IL-28B),Interleukin-28C (IL-28C)
|
| Uniprot Accession |
Q8IZI9
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSCAFG00845004745, ENSG00000197110, ENSMMUG00000018760
|
Pre-made viral vector of IL-28B/IFNL3 cDNA Clones/ORF Plasmid
IL-28B/IFNL3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo282617 | Pre-made Human IFNL3/IL28B/IL28C siRNA oligo Duplex | 282617 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695997 | Pre-made Cynomolgus/Rhesus macaque IFNL3/IL28A/IL28B siRNA oligo Duplex | 695997 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119870346 | Pre-made Dog/Canine IFNL3 siRNA oligo Duplex | 119870346 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
IL-28B/IFNL3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T55242-Ab | Human | Anti-Human IL-28B/IFNL3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T55242-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-28B/IFNL3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T55242-Ab | Dog/Canine | Anti-Dog/Canine IL-28B/IFNL3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-28B/IFNL3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T55242-Ag | Human | Human IL-28B/IFNL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T55242-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-28B/IFNL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T55242-Ag | Dog/Canine | Dog/Canine IL-28B/IFNL3 recombinant protein | Mammalian cell | Detail |
