Explore KCNQ5 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
| Target ID |
GM-T55068
|
| Target Name |
KCNQ5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
56479
|
| Gene ID |
100071357 (Equus caballus), 101092113 (Felis catus), 226922 (Mus musculus), 259273 (Rattus norvegicus)
474965 (Canis lupus familiaris), 56479 (Homo sapiens), 613605 (Bos taurus), 715426 (Macaca mulatta)
|
| Target Alternative Names |
7730402H11,9230107O05Rik,D1Mgi1,KCNQ5,KQT-like 5,Kcnq5,Kcnq5l,Kv7.5,MRD46,Potassium channel subunit alpha KvLQT5,Potassium voltage-gated channel subfamily KQT member 5,Voltage-gated potassium channel subunit Kv7.5
|
| Uniprot Accession |
Q9JK45,Q9NR82
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Cholinergic synapse
|
| Gene Ensembl |
ENSECAG00000011900, ENSMUSG00000028033, ENSCAFG00845011313, ENSG00000185760, ENSBTAG00000007791, ENSMMUG00000015320
|
| Target Classification |
Ion Channel
|
KCNQ5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo56479 | Pre-made Human KCNQ5/Kv7.5/MRD46 siRNA oligo Duplex | 56479 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo259273 | Pre-made Rat Kcnq5/Kcnq5l siRNA oligo Duplex | 259273 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo226922 | Pre-made Mouse Kcnq5/D1Mgi1/7730402H11 siRNA oligo Duplex | 226922 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715426 | Pre-made Cynomolgus/Rhesus macaque KCNQ5 siRNA oligo Duplex | 715426 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092113 | Pre-made Cat/Feline KCNQ5 siRNA oligo Duplex | 101092113 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474965 | Pre-made Dog/Canine KCNQ5 siRNA oligo Duplex | 474965 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613605 | Pre-made Bovines/Cattle KCNQ5 siRNA oligo Duplex | 613605 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071357 | Pre-made Equine/Horse KCNQ5 siRNA oligo Duplex | 100071357 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNQ5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T55068-Ab | Human | Anti-Human KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T55068-Ab | Rat | Anti-Rat KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T55068-Ab | Mouse | Anti-Mouse KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T55068-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T55068-Ab | Cat/Feline | Anti-Cat/Feline KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T55068-Ab | Dog/Canine | Anti-Dog/Canine KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T55068-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T55068-Ab | Equine/Horse | Anti-Equine/Horse KCNQ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNQ5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T55068-Ag | Human | Human KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T55068-Ag | Rat | Rat KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T55068-Ag | Mouse | Mouse KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T55068-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T55068-Ag | Cat/Feline | Cat/Feline KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T55068-Ag | Dog/Canine | Dog/Canine KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T55068-Ag | Bovines/Cattle | Bovines/Cattle KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T55068-Ag | Equine/Horse | Equine/Horse KCNQ5 VLP (virus-like particle) | HEK293 | Products Developing |
